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Synthetic biology in mammalian cells: next generation research tools and therapeutics
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PubMed
title
Synthetic biology in mammalian cells: next generation research tools and therapeutics
(English)
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stated in
PubMed
main subject
synthetic biology
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based on heuristic
inferred from title
author
Pamela Silver
series ordinal
4
object named as
Pamela A. Silver
1 reference
stated in
Crossref
author name string
Florian Lienert
series ordinal
1
1 reference
stated in
Crossref
Jason J. Lohmueller
series ordinal
2
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stated in
Crossref
Abhishek Garg
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
February 2014
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stated in
PubMed
published in
Nature Reviews Molecular Cell Biology
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stated in
PubMed
volume
15
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stated in
PubMed
issue
2
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stated in
PubMed
page(s)
95-107
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PubMed
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retrieved
28 September 2017
A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Engineering biological systems with synthetic RNA molecules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Synthetic chromosome arms function in yeast and generate phenotypic diversity by design
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Multi-input RNAi-based logic circuit for identification of specific cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Small-molecule displacement of a cryptic degron causes conditional protein degradation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Engineering dendritic cells to enhance cancer immunotherapy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Assembly of custom TALE-type DNA binding domains by modular cloning
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Tunable signal processing in synthetic MAP kinase cascades
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
A tunable dual-promoter integrator for targeting of cancer cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
An engineered mammalian band-pass network
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Rationally designed logic integration of regulatory signals in mammalian cells
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Live attenuated influenza virus vaccines by computer-aided rational design
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Photomodulation of protein trans-splicing through backbone photocaging of the DnaE split intein
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Designing customized cell signalling circuits
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Cell penetrating elastin-like polypeptides for therapeutic peptide delivery
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Synthetic biology: applications come of age
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Synthetic design of strong promoters
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Genome engineering
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
An auxin-based degron system for the rapid depletion of proteins in nonplant cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
A tunable synthetic mammalian oscillator
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Global protein stability profiling in mammalian cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Enhancement of cell type specificity by quantitative modulation of a chimeric ligand
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
A universal RNAi-based logic evaluator that operates in mammalian cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
A synthetic time-delay circuit in mammalian cells and mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Foundations for engineering biology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Hysteresis in a synthetic mammalian gene network
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Conditional protein splicing: a new tool to control protein structure and function in vitro and in vivo.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Combinatorial synthesis of genetic networks
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Microencapsulated islets as bioartificial endocrine pancreas
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 September 2017
Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 September 2017
Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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31 May 2018
Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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31 May 2018
Dynamics and memory of heterochromatin in living cells.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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31 May 2018
Engineering and identifying supercharged proteins for macromolecule delivery into mammalian cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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31 May 2018
Effective gene silencing by multilayered siRNA-coated gold nanoparticles
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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31 May 2018
A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
31 May 2018
Optogenetic control of protein kinase activity in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
Precise and reliable gene expression via standard transcription and translation initiation elements
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 November 2018
Chemical synthesis of the mouse mitochondrial genome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
Self-sufficient control of urate homeostasis in mice by a synthetic circuit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
Anti-glycophorin single-chain Fv fusion to low-affinity mutant erythropoietin improves red blood cell-lineage specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
A yeast synthetic network for in vivo assessment of reverse-engineering and modeling approaches
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
Functional protein delivery into neurons using polymeric nanoparticles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
BioLogic gates enable logical transcription control in mammalian cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
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28 November 2018
Intracellular delivery of proteins with a new lipid-mediated delivery system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032074
retrieved
28 November 2018
Lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNRM3738
retrieved
31 March 2020
Cytosine methylation targetted to pre-determined sequences
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNRM3738
retrieved
31 March 2020
Antibody-cytokine fusion proteins: applications in cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRM3738
retrieved
31 March 2020
Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNRM3738
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31 March 2020
Identifiers
DOI
10.1038/NRM3738
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
609186
Dimensions Publication ID
1042323714
0 references
Fatcat ID
release_azwhif4m7rhsjp55yeae75tl2m
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/azwhif4m7rhsjp55yeae75tl2m
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
609186
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
609186
PMCID
4032074
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
609186
PubMed ID
24434884
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
609186
Springer Nature article ID
10.1038/nrm3738
0 references
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