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The immune system as a sensor of the metabolic state
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title
The immune system as a sensor of the metabolic state
(English)
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author name string
Justin I. Odegaard
series ordinal
1
1 reference
stated in
Crossref
Ajay Chawla
series ordinal
2
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
18 April 2013
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stated in
PubMed
published in
Immunity
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stated in
PubMed
volume
38
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stated in
PubMed
issue
4
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stated in
PubMed
page(s)
644-54
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PubMed
cites work
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
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Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis
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Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation
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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
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Inflammation and metabolic disorders
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Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
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Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis
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Obesity induces a phenotypic switch in adipose tissue macrophage polarization
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Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
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National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants
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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
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CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
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Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
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7 April 2017
Adipocytes as regulators of energy balance and glucose homeostasis
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7 April 2017
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
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Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
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IKK-beta links inflammation to obesity-induced insulin resistance
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HIF-1alpha is essential for myeloid cell-mediated inflammation
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A central role for JNK in obesity and insulin resistance
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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
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Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages
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28 September 2017
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice
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Adaptive thermogenesis in adipocytes: is beige the new brown?
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Metabolism of inflammation limited by AMPK and pseudo-starvation
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Direct control of hepatic glucose production by interleukin-13 in mice.
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Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production.
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Evolution of vertebrate immunity
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28 September 2017
Inflammasomes and their roles in health and disease
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28 September 2017
Biomarkers and immune-modulating therapies for type 2 diabetes
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Tissue-specific insulin signaling, metabolic syndrome, and cardiovascular disease
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Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
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Natural killer T cells in adipose tissue prevent insulin resistance
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Leukocyte set points in metabolic disease
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In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding
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28 September 2017
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Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity
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Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance
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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
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28 September 2017
A systems biology approach to nutritional immunology - focus on innate immunity
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28 September 2017
Hormonal regulation of hepatic glucose production in health and disease
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28 September 2017
Regulation of the antimicrobial response by NLR proteins.
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28 September 2017
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28 September 2017
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
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28 September 2017
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28 September 2017
Distribution and development of brown adipocytes in the murine and human adipose organ
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28 September 2017
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism
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28 September 2017
C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis
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28 September 2017
Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1
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28 September 2017
Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance
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28 September 2017
Normalization of obesity-associated insulin resistance through immunotherapy
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28 September 2017
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
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28 September 2017
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
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28 September 2017
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28 September 2017
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28 September 2017
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance
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28 September 2017
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28 September 2017
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28 September 2017
IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes
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31 May 2018
Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages
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31 May 2018
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis.
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31 May 2018
Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.
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31 May 2018
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.
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28 November 2018
CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice
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based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.IMMUNI.2013.04.001
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3074936
OpenCitations bibliographic resource ID
3074936
1 reference
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Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3074936
PMCID
3663597
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3074936
PubMed ID
23601683
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3074936
ResearchGate publication ID
236250392
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