(Q27305890)

26 June 2017

title

Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling (English)

1 reference

26 June 2017

0 references

Andrew Archibald

1

1 reference

26 June 2017

Maia Al-Masri

series ordinal

2

1 reference

26 June 2017

Alyson Liew-Spilger

series ordinal

3

1 reference

26 June 2017

Luke McCaffrey

series ordinal

4

1 reference

26 June 2017

publication date

12 August 2015

1 reference

Molecular Biology of the Cell

26 June 2017

published in

1 reference

26 June 2017

volume

26

1 reference

26 June 2017

issue

20

1 reference

26 June 2017

page(s)

3578-3595

1 reference

describes a project that uses

26 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4603929/fullTextXML

inferred from PubMed Central ID database lookup

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Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

21 March 2017

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The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

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28 September 2017

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28 September 2017

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Association of PKCζ expression with clinicopathological characteristics of breast cancer

28 September 2017

1 reference

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A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis

28 September 2017

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28 September 2017

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Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation

28 September 2017

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28 September 2017

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Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases

28 September 2017

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Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.

28 September 2017

1 reference

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GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.

28 September 2017

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28 September 2017

1 reference

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28 September 2017

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Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis

28 September 2017

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Protein kinases of the Hippo pathway: regulation and substrates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Splice variant PRKC-ζ(-PrC) is a novel biomarker of human prostate cancer

28 September 2017

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Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Collective and single cell behavior in epithelial contact inhibition.

28 September 2017

1 reference

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Epithelial cell polarity, stem cells and cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Coordinating developmental signaling: novel roles for the Hippo pathway.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Repression of cancer cell senescence by PKCι.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

The Hippo pathway and apico-basal cell polarity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Different responses in transformation of MDCK cells in 2D and 3D culture by v-Src as revealed by microarray techniques, RT-PCR and functional assays

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

YAP regulates neural progenitor cell number via the TEA domain transcription factor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Targeting the oncogenic protein kinase Ciota signalling pathway for the treatment of cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Angiomotin expression promotes hemangioendothelioma invasion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Patterns of protein kinase C isoenzyme expression in transitional cell carcinoma of bladder. Relation to degree of malignancy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Transformation of epithelial Madin-Darby canine kidney cells with p60(v-src) induces expression of membrane-type 1 matrix metalloproteinase and invasiveness

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Activated Ras protein accelerates cell cycle progression to perturb Madin-Darby canine kidney cystogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

A molecular network for de novo generation of the apical surface and lumen

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Characterization of the interface between normal and transformed epithelial cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4603929

Expression of P-aPKC-iota, E-cadherin, and beta-catenin related to invasion and metastasis in hepatocellular carcinoma

31 May 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

ROCK-mediated contractility, tight junctions and channels contribute to the conversion of a preapical patch into apical surface during isochoric lumen initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

aPKCλ/ι is a beneficial prognostic marker for pancreatic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

Loss of APKC expression independently predicts tumor recurrence in superficial bladder cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

The overexpression and altered localization of the atypical protein kinase C λ/ι in breast cancer correlates with the pathologic type of these tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-05-0265

Alteration in the expression of protein kinase C isoforms in human hepatocellular carcinoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26269582

12 December 2020

inferred from PubMed ID database lookup

Expression of protein kinase C isoforms in cancerous breast tissue and adjacent normal breast tissue

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26269582

12 December 2020

inferred from PubMed ID database lookup

Expression patterns of protein kinase C isoenzymes are characteristically modulated in chronic pancreatitis and pancreatic cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26269582

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1091/MBC.E15-05-0265

1 reference

OpenCitations bibliographic resource ID

26 June 2017

4762102

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4762102

1 reference