(Q27308143)

25 June 2017

title

Seizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in mice (English)

1 reference

25 June 2017

0 references

John J McMahon

1

1 reference

25 June 2017

Wilson Yu

2

1 reference

25 June 2017

Jun Yang

3

1 reference

25 June 2017

Haihua Feng

4

1 reference

25 June 2017

Meghan Helm

5

1 reference

25 June 2017

Elizabeth McMahon

6

1 reference

25 June 2017

Xinjun Zhu

7

1 reference

25 June 2017

Damian Shin

8

1 reference

25 June 2017

Yunfei Huang

9

1 reference

25 June 2017

language of work or name

English

0 references

publication date

12 October 2014

1 reference

25 June 2017

published in

Neurobiology of Disease

1 reference

25 June 2017

volume

73

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25 June 2017

page(s)

296-306

1 reference

describes a project that uses

25 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4394017/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.

28 September 2017

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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

28 September 2017

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The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway

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Rapamycin attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy

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Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

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Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin

28 September 2017

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Risk and correlates of autism spectrum disorder in children with epilepsy: a community-based study

28 September 2017

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Correlation between EEG abnormalities and symptoms of autism spectrum disorder (ASD)

28 September 2017

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Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy

28 September 2017

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28 September 2017

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28 September 2017

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Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy

28 September 2017

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Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.

28 September 2017

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Postnatal lesion evidence against a primary role for the corpus callosum in mouse sociability

28 September 2017

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Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Seizure-induced 5-HT release and chronic impairment of serotonergic function in rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Effects of tryptophan depletion in drug-free adults with autistic disorder

31 May 2018

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Whole blood serotonin in autistic and normal subjects

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Withdrawal from chronic treatment with (+/-)-DOI causes super-sensitivity to 5-HT2 receptor-induced head-twitch behaviour in mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Can EEG characteristics predict development of epilepsy in autistic children?

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

MRI characterization and longitudinal study of focal cerebellar lesions in a young tuberous sclerosis cohort

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

A double-blind placebo-controlled trial of fluoxetine for repetitive behaviors and global severity in adult autism spectrum disorders

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Fluoxetine but not risperidone increases sociability in the BTBR mouse model of autism

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Epilepsy and EEG paroxysmal abnormalities in autism spectrum disorders

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Lipid raft-targeted Akt promotes axonal branching and growth cone expansion via mTOR and Rac1, respectively

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

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28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Characterization of autism in young children with tuberous sclerosis complex

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Cerebellar lesions in tuberous sclerosis complex: neurobehavioral and neuroimaging correlates

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Platelet serotonin levels in pervasive developmental disorders and mental retardation: diagnostic group differences, within-group distribution, and behavioral correlates

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Infantile spasms in Down syndrome--effects of delayed anticonvulsive treatment.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Modulation of 5-HT(2A) receptor-mediated head-twitch behaviour in the rat by 5-HT(2C) receptor agonists

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Whole blood serotonin and plasma beta-endorphin in autistic probands and their first-degree relatives.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394017

Tryptophan hydroxylase 2 (TPH2) haplotypes predict levels of TPH2 mRNA expression in human pons

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25315683

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NBD.2014.10.004

1 reference

25 June 2017

0 references

1 reference