(Q27308754)

26 June 2017

title

IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis (English)

1 reference

cancer-associated fibroblast

26 June 2017

main subject

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Florian Greten

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Paul K Ziegler

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

language of work or name

English

0 references

publication date

30 November 2015

1 reference

Journal of Experimental Medicine

26 June 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

212

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

2253-2266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

8 June 2020

cites work

1 reference

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An overview of the c-MET signaling pathway

21 March 2017

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A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA

21 March 2017

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 March 2017

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 March 2017

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Accessories to the crime: functions of cells recruited to the tumor microenvironment

7 April 2017

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

7 April 2017

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

7 April 2017

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TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

7 April 2017

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IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer

7 April 2017

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NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair

28 September 2017

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Fibroblast heterogeneity in the cancer wound

28 September 2017

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Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis.

28 September 2017

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Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

28 September 2017

1 reference

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Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

28 September 2017

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Regulation of hepatocyte growth factor expression by NF-κB and PPARγ in adipose tissue

28 September 2017

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TGF-beta in CAF-mediated tumor growth and metastasis

28 September 2017

1 reference

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From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers

28 September 2017

1 reference

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Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression

28 September 2017

1 reference

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A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3.

28 September 2017

1 reference

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Tpl2 kinase signal transduction in inflammation and cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Hepatocyte growth factor twenty years on: Much more than a growth factor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Jekyll and Hyde: the role of the microenvironment on the progression of cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

MET signalling: principles and functions in development, organ regeneration and cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Oxidative stress promotes myofibroblast differentiation and tumour spreading

28 September 2017

1 reference

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Activation of fibroblasts in cancer stroma

28 September 2017

1 reference

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Hepatocyte growth factor inhibits CNS autoimmunity by inducing tolerogenic dendritic cells and CD25+Foxp3+ regulatory T cells

28 September 2017

1 reference

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NF-kappaB as a critical link between inflammation and cancer

28 September 2017

1 reference

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Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7.

28 September 2017

1 reference

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Colon cancer metastasis: MACC1 and Met as metastatic pacemakers

28 September 2017

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Regulation of TGF-beta signaling by Smad7.

28 September 2017

1 reference

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Cancer-associated fibroblasts and tumor growth--bystanders turning into key players

28 September 2017

1 reference

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PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Opposing functions of IKKbeta during acute and chronic intestinal inflammation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Stromal myofibroblasts are drivers of invasive cancer growth

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Smad7 sensitizes tumor necrosis factor induced apoptosis through the inhibition of antiapoptotic gene expression by suppressing activation of the nuclear factor-kappaB pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Interferon-beta mediates stromal cell rescue of T cells from apoptosis.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Interleukin-1beta up-regulation of Smad7 via NF-kappaB activation in human chondrocytes.

31 May 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20150576

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20150576

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20150576

Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20150576

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20150576

Interleukin-1beta increases RANTES gene expression and production in synovial fibroblasts from human temporomandibular joint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20150576

Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20150576

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

Expression of the hepatocyte growth factor and c-Met in colon cancer: correlation with clinicopathological features and overall survival

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4689166

TGFβ1 and TNFα Secreted by Mast Cells Stimulated via the FcϵRI Activate Fibroblasts for High-Level Production of Monocyte Chemoattractant Protein-1 (MCP-1)

28 November 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20150576

GM-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8, IL-10, ICAM-1 and VCAM-1 gene expression and cytokine production in human duodenal fibroblasts stimulated with lipopolysaccharide, IL-1 alpha and TNF-alpha

21 January 2018

1 reference

12 December 2020

Hepatocyte growth factor significantly suppresses collagen-induced arthritis in mice

1 reference

12 December 2020

Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression

1 reference

12 December 2020

Epidermal growth factor synergistically enhances interleukin-8 production in human gingival fibroblasts stimulated with interleukin-1beta

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20150576

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

8 June 2020

2452108

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2452108

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26621452%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference