(Q27485335)

2

0 references

Joanne P Graham

3

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Shella A Fuhrman

4

0 references

Chau Doan

5

0 references

Hans Parge

6

0 references

Michael Hickey

7

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Jingjin Gao

8

0 references

Xiu Yu

9

0 references

Fannie Chau

10

0 references

Javier Gonzalez

11

0 references

Hui Li

12

0 references

Cristina Lewis

13

0 references

Amy K Patick

14

0 references

Rohit Duggal

Antimicrobial Agents and Chemotherapy

15

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language of work or name

English

0 references

publication date

February 2008

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published in

0 references

volume

52

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issue

2

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page(s)

675-83

0 references

cites work

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Molecular Mechanism of a Thumb Domain Hepatitis C Virus Nonnucleoside RNA-Dependent RNA Polymerase Inhibitor

20 March 2017

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Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus

20 March 2017

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Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro

20 March 2017

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Resistance Profile of a Hepatitis C Virus RNA-Dependent RNA Polymerase Benzothiadiazine Inhibitor

20 March 2017

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Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme

20 March 2017

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20 March 2017

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20 March 2017

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Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

20 March 2017

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20 March 2017

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20 March 2017

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7 April 2017

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Allosteric inhibitors of hepatitis C polymerase: discovery of potent and orally bioavailable carbon-linked dihydropyrones

7 April 2017

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Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.

29 September 2017

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Allosteric inhibition of the hepatitis C virus NS5B RNA dependent RNA polymerase

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29 September 2017

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Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034.

29 September 2017

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Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations

29 September 2017

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Binding site characterization and resistance to a class of non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase

29 September 2017

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Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro

29 September 2017

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A review of HIV-1 resistance to the nucleoside and nucleotide inhibitors

29 September 2017

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29 September 2017

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Mechanism of action and antiviral activity of benzimidazole-based allosteric inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.

29 September 2017

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29 September 2017

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29 September 2017

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Telaprevir and pegylated interferon-alpha-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients

29 September 2017

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Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir

27 November 2018

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Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors

27 November 2018

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In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2224781

High-dose ribavirin in combination with standard dose peginterferon for treatment of patients with chronic hepatitis C.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2224781

HCV NS5b RNA-dependent RNA polymerase inhibitors: from alpha,gamma-diketoacids to 4,5-dihydroxypyrimidine- or 3-methyl-5-hydroxypyrimidinonecarboxylic acids. Design and synthesis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2224781

In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2224781

Anemia in the Treatment of Hepatitis C Virus Infection

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2224781

Natural history of hepatitis C

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18070954

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18070954