(Q27633719)

1

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E D Thuresson

2

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K M Lakkides

3

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C J Rieke

4

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R Micielli

5

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W L Smith

6

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R M Garavito

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

5 October 2001

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published in

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volume

276

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issue

40

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page(s)

37547-55

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cites work

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Interleukin-1 beta induces cytosolic phospholipase A2 and prostaglandin H synthase in rheumatoid synovial fibroblasts. Evidence for their roles in the production of prostaglandin E2.

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Interleukin-1beta-induced cyclooxygenase-2 expression requires activation of both c-Jun NH2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells

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Prostaglandin G/H synthase isoenzyme 2 expression in fibroblasts: regulation by dexamethasone, mitogens, and oncogenes

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v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor

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Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum

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The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

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Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2

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The productive conformation of arachidonic acid bound to prostaglandin synthase

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Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. Formation of 12-hydroxy-(9Z, 13E/Z, 15Z)- octadecatrienoic acids from alpha-linolenic acid

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Cyclooxygenase 2 inhibitors: discovery, selectivity and the future

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Comparison of Hydroperoxide Initiator Requirements for the Cyclooxygenase Activities of Prostaglandin H Synthase-1 and −2

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Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases

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Spectroscopic evidence for reaction of prostaglandin H synthase-1 tyrosyl radical with arachidonic acid.

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Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells

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Prostaglandins in human semen during fish oil ingestion: evidence for in vivo cyclooxygenase inhibition and appearance of novel trienoic compounds.

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Cyclooxygenase-catalyzed formation of 9-hydroxylinoleic acid by guinea pig alveolar macrophages under non-stimulated conditions

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The membrane binding domains of prostaglandin endoperoxide H synthases 1 and 2. Peptide mapping and mutational analysis

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Prostaglandin G2 levels during reaction of prostaglandin H synthase with arachidonic acid

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Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.

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The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase

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