(Q27640584)

English

Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities

scientific article (publication date: 23 October 2014)

Statements

Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities (English)
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Pedro Soares
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Salvatore Scaffidi
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Ipek Birced
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Sarah Hewitt
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David M Dias
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23 October 2014
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57
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20
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8657-63
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