(Q27643516)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Development of calpain-specific inactivators by screening of positional scanning epoxide libraries (English)

1 reference

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24 December 2019

2

1 reference

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24 December 2019

Robert L. Campbell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Steven Verhelst

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

8

Matthew Bogyo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

Dominic Cuerrier

1

1 reference

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24 December 2019

Jacqueline Kelly

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Bilge Yoruk

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Doron Greenbaum

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Peter L Davies

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

language of work or name

English

0 references

publication date

11 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

24 December 2019

published in

1 reference

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24 December 2019

volume

282

1 reference

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24 December 2019

issue

13

1 reference

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24 December 2019

page(s)

9600-9611

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

Neurotoxicity induces cleavage of p35 to p25 by calpain

24 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Calpain-induced Bax-cleavage product is a more potent inducer of apoptotic cell death than wild-type Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Cutting to the chase: calpain proteases in cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Calpain as a multi-site regulator of cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Spatial resolution of calpain-catalyzed proteolysis in focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Linkage of calpain 10 to type 2 diabetes: the biological rationale

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Isolation of two novel genes, down-regulated in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Neuroprotection with a calpain inhibitor in a model of focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

The calpain family and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Cysteine proteinase inhibitors and ras gene products share the same biological activities including transforming activity toward NIH3T3 mouse fibroblasts and the differentiation-inducing activity toward PC12 rat pheochromocytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

D-amino acid containing, high-affinity inhibitors of recombinant human calpain I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

A Ca(2+) switch aligns the active site of calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Calpain activation by cooperative Ca2+ binding at two non-EF-hand sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: the importance of primed side interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Calpain silencing by a reversible intrinsic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Calpain inhibition by alpha-ketoamide and cyclic hemiacetal inhibitors revealed by X-ray crystallography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Small molecule affinity fingerprinting. A tool for enzyme family subclassification, target identification, and inhibitor design

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Design, synthesis, and evaluation of aza-peptide epoxides as selective and potent inhibitors of caspases-1, -3, -6, and -8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Recombinant calpain II: improved expression systems and production of a C105A active-site mutant for crystallography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Solid-phase synthesis of double-headed epoxysuccinyl activity-based probes for selective targeting of papain family cysteine proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Irreversible inhibitors of serine, cysteine, and threonine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Cathepsin B, Cathepsin H, and cathepsin L

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

21 January 2018

Human liver cathepsin L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

The integration of macromolecular diffraction data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

The CCP4 molecular-graphics project

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Efficient anisotropic refinement of macromolecular structures using FFT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Chemical approaches for functionally probing the proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

A role for the protease falcipain 1 in host cell invasion by the human malaria parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Calpain inhibition by peptide epoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

On the sequential determinants of calpain cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

Spherically averaged phased translation function and its application to the search for molecules and fragments in electron-density maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610372200

21 January 2018

Identifiers

DOI

10.1074/JBC.M610372200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218315%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference