(Q27654224)

4

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author name string

Eniko Takács

1

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Orsolya Barabás

2

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Beáta G Vértessy

Uracil in DNA--occurrence, consequences and repair

5

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language of work or name

English

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publication date

4 March 2009

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published in

FEBS Letters

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volume

583

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issue

5

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page(s)

865-71

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cites work

1 reference

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Crystal structure of a dUTPase

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dUTPase as a platform for antimalarial drug design: structural basis for the selectivity of a class of nucleoside inhibitors.

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Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.

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dUTPase from Escherichia coli; high-level expression and one-step purification.

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Kinetic characterization of dUTPase from Escherichia coli.

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Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

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Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits

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PRIMUS: a Windows PC-based system for small-angle scattering data analysis

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Specific derivatization of the active site tyrosine in dUTPase perturbs ligand binding to the active site

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A tradeoff between protein stability and conformational mobility in homotrimeric dUTPases

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Principles of protein-protein recognition

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The CCP4 suite: programs for protein crystallography

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PQS: a protein quaternary structure file server

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PIC: Protein Interactions Calculator

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Altered subunit communication in subfamilies of trimeric dUTPases

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Trifluoroethanol and colleagues: cosolvents come of age. Recent studies with peptides and proteins.

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Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase

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Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor

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Crystal structure of dUTPase from equine infectious anaemia virus; active site metal binding in a substrate analogue complex

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An extended hudrophobic core induces EF-hand swapping

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Structure of the forkhead domain of FOXP2 bound to DNA

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Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing

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Global rigid body modeling of macromolecular complexes against small-angle scattering data

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Identification of sequence determinants of human nuclear dUTPase isoform localization

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Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme

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Structural characterization of flexible proteins using small-angle X-ray scattering

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Improved R-factors for diffraction data analysis in macromolecular crystallography

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