(Q27660497)

2

0 references

Yaya Wang

3

0 references

Genhong Cheng

4

0 references

Hao Wu

Structural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2

5

0 references

publication date

9 April 2010

0 references

published in

Molecular Cell

0 references

volume

38

0 references

issue

1

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page(s)

101-13

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855162

E2 interaction and dimerization in the crystal structure of TRAF6

20 March 2017

1 reference

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Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

20 March 2017

1 reference

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c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

20 March 2017

1 reference

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TNF-alpha induces two distinct caspase-8 activation pathways

20 March 2017

1 reference

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IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

20 March 2017

1 reference

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IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

20 March 2017

1 reference

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Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

20 March 2017

1 reference

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XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization

20 March 2017

1 reference

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Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases

20 March 2017

1 reference

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Structural basis for self-association and receptor recognition of human TRAF2

20 March 2017

1 reference

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

20 March 2017

1 reference

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

20 March 2017

1 reference

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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

20 March 2017

1 reference

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Shape complementarity at protein/protein interfaces

20 March 2017

1 reference

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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

20 March 2017

1 reference

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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

20 March 2017

1 reference

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A hot spot of binding energy in a hormone-receptor interface

20 March 2017

1 reference

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Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

7 April 2017

1 reference

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Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

7 April 2017

1 reference

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

7 April 2017

1 reference

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TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

7 April 2017

1 reference

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Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation

29 September 2017

1 reference

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TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-kappaB.

29 September 2017

1 reference

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Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

29 September 2017

1 reference

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IAP-targeted therapies for cancer

29 September 2017

1 reference

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cIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligand

29 September 2017

1 reference

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Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

29 September 2017

1 reference

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Targeting TRAfs for therapeutic intervention

29 September 2017

1 reference

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TRAF1 and its biological functions

29 September 2017

1 reference

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A dual role for the API2 moiety in API2-MALT1-dependent NF-kappaB activation: heterotypic oligomerization and TRAF2 recruitment

29 September 2017

1 reference

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CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

29 September 2017

1 reference

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Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation

29 September 2017

1 reference

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Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855162

Gene targeting in the analysis of mammalian apoptosis and TNF receptor superfamily signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855162

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855162

The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855162

Mass spectrometric analysis of tumor necrosis factor receptor-associated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855162

The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855162

TRAF1 is a TNF inducible regulator of NF-kappaB activation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855162

TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20385093

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20385093

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2010.03.009

1 reference

1809455

1809455

1 reference

1 reference

1 reference