(Q27683462)

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Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness

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14 March 2020

Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness (English)

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14 March 2020

infectious disease

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Trypanosoma brucei

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African trypanosomiasis

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1

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14 March 2020

Frederick S Buckner

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14 March 2020

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Wim G J Hol

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14 March 2020

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Jessica E Kim

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14 March 2020

Allan B Wetzel

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14 March 2020

Will J de van der Schueren

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14 March 2020

Sayaka Shibata

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14 March 2020

Ranae M Ranade

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14 March 2020

Jiyun Liu

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14 March 2020

Zhongsheng Zhang

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14 March 2020

J Robert Gillespie

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14 March 2020

Christophe L M J Verlinde

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14 March 2020

Erkang Fan

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14 March 2020

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17 April 2014

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14 March 2020

PLoS Neglected Tropical Diseases

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14 March 2020

8

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14 March 2020

4

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14 March 2020

e2775

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14 March 2020

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Creative Commons Attribution 4.0 International

17 April 2014

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ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

The Genome of the African Trypanosome Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

Overview of the CCP4 suite and current developments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

Features and development of Coot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

Phasercrystallographic software

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

20 March 2017

Control of neglected tropical diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

7 April 2017

Aminoacyl-tRNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

7 April 2017

Induced resistance to methionyl-tRNA synthetase inhibitors in Trypanosoma brucei is due to overexpression of the target.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Aminoacyl-tRNA synthetase inhibitors as potential antibiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Eliminating human African trypanosomiasis: where do we stand and what comes next?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

New aminoacyl-tRNA synthetase inhibitors as antibacterial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Variable sensitivity to bacterial methionyl-tRNA synthetase inhibitors reveals subpopulations of Streptococcus pneumoniae with two distinct methionyl-tRNA synthetase genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

29 September 2017

Human African trypanosomiasis

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0002775

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990509

27 November 2018

Inhibition of methionyl-tRNA synthetase by REP8839 and effects of resistance mutations on enzyme activity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0002775

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0002775

21 January 2018

Structural basis for anticodon recognition by methionyl-tRNA synthetase.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0002775

21 January 2018

Identifiers

10.1371/JOURNAL.PNTD.0002775

2 references

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14 March 2020

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Consolidated OpenCitations Corpus – April 2017

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14 March 2020

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Consolidated OpenCitations Corpus – April 2017

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14 March 2020

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