(Q27688974)

8

object named as

Andrew Leaver-Fay

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author name string

Steven M Lewis

1

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Xiufeng Wu

2

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Anna Pustilnik

3

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Arlene Sereno

4

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Flora Huang

5

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Heather L Rick

6

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Gurkan Guntas

7

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Eric M Smith

9

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Carolyn Ho

10

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Christophe Hansen-Estruch

11

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Aaron K Chamberlain

12

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Stephanie M Truhlar

13

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Elaine M Conner

14

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Shane Atwell

15

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Stephen J Demarest

Bispecific antibodies for cancer therapy: the light at the end of the tunnel?

17

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publication date

February 2014

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published in

Nature Biotechnology

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volume

32

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issue

2

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page(s)

191-8

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cites work

1 reference

MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival

20 April 2017

1 reference

Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair

20 April 2017

1 reference

Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site

20 April 2017

1 reference

Computational redesign of endonuclease DNA binding and cleavage specificity

20 April 2017

1 reference

Matuzumab Binding to EGFR Prevents the Conformational Rearrangement Required for Dimerization

20 April 2017

1 reference

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

20 April 2017

1 reference

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

20 April 2017

1 reference

Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations

20 April 2017

1 reference

RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite

20 April 2017

1 reference

Predicting protein structures with a multiplayer online game

20 April 2017

1 reference

Phasercrystallographic software

20 April 2017

1 reference

Refinement of macromolecular structures by the maximum-likelihood method

20 April 2017

1 reference

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

20 April 2017

1 reference

An introduction to data reduction: space-group determination, scaling and intensity statistics

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNBT.2797

Targeting T cells with bispecific antibodies for cancer therapy

20 April 2017

1 reference

12 December 2020

'Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization

1 reference

12 December 2020

VH/VL interface engineering to promote selective expression and inhibit conformational isomerization of thrombopoietin receptor agonist single-chain diabody.

1 reference

12 December 2020

An efficient route to human bispecific IgG.

1 reference

12 December 2020

Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo

1 reference

12 December 2020

Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies.

1 reference

12 December 2020

The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells.

1 reference

12 December 2020

Automated design of specificity in molecular recognition

1 reference

12 December 2020

The Rossmann Fourier autoindexing algorithm in MOSFLM

1 reference

12 December 2020

An unfolded CH1 domain controls the assembly and secretion of IgG antibodies.

1 reference

12 December 2020

PCR-based gene synthesis and protein NMR spectroscopy

1 reference

12 December 2020

Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTbetaR.

1 reference

12 December 2020

Anchored design of protein-protein interfaces

1 reference

12 December 2020

An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies

1 reference

12 December 2020

Enhancing antibody Fc heterodimer formation through electrostatic steering effects: applications to bispecific molecules and monovalent IgG.

1 reference

12 December 2020

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.

1 reference

12 December 2020

Contributions of a highly conserved VH/VL hydrogen bonding interaction to scFv folding stability and refolding efficiency

1 reference

12 December 2020

Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity

1 reference

12 December 2020

Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies

1 reference

12 December 2020

Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

1 reference

12 December 2020

A generic program for multistate protein design

1 reference

12 December 2020

Antibody therapeutics, antibody engineering, and the merits of protein stability

1 reference

12 December 2020

Bispecific antibody to ErbB2 overcomes trastuzumab resistance through comprehensive blockade of ErbB2 heterodimerization.

1 reference

12 December 2020

Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics

1 reference

12 December 2020

A broad range of Fab stabilities within a host of therapeutic IgGs.

1 reference

12 December 2020

Scientific benchmarks for guiding macromolecular energy function improvement

1 reference

12 December 2020

Reorienting the Fab domains of trastuzumab results in potent HER2 activators

1 reference

12 December 2020

Design of protein-interaction specificity gives selective bZIP-binding peptides.

1 reference

12 December 2020

Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies

1 reference

12 December 2020