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Lessons from mathematically modeling the NF-κB pathway
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title
Lessons from mathematically modeling the NF-κB pathway
(English)
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PubMed
main subject
NF-κB
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author name string
Basak S
series ordinal
1
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PubMed
Behar M
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2
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PubMed
Hoffmann A
series ordinal
3
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publication date
March 2012
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published in
Immunological Reviews
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PubMed
volume
246
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PubMed
issue
1
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PubMed
page(s)
221-38
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PubMed
cites work
Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles
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Generation and activation of multiple dimeric transcription factors within the NF-kappaB signaling system
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A fourth IkappaB protein within the NF-kappaB signaling module
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Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL
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Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B
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Drug inhibition profile prediction for NFκB pathway in multiple myeloma
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The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-kappaB target genes
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Modeling the NF-κB mediated inflammatory response predicts cytokine waves in tissue
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IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response
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Flexible Regions within IκBα Create the Ubiquitin-independent Degradation Signal
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Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-kappaB signaling-induced gene expression responses in inflammation
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Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs
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The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes
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Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity
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Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription
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Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.
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Integrating computational and biochemical studies to explore mechanisms in NF-{kappa}B signaling
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New regulators of NF-kappaB in inflammation
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29 September 2017
Crosstalk via the NF-kappaB signaling system
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29 September 2017
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Minimal model of spiky oscillations in NF-kappaB signaling.
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IkappaBepsilon provides negative feedback to control NF-kappaB oscillations, signaling dynamics, and inflammatory gene expression.
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Circuitry of nuclear factor kappaB signaling
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Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway
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Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma
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Identifiers
DOI
10.1111/J.1600-065X.2011.01092.X
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3110697
OpenCitations bibliographic resource ID
3110697
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3110697
PMC publication ID
3343698
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3110697
PubMed publication ID
22435558
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3110697
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