(Q27937390)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity (English)

2 references

1 December 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

0 references

1 reference

Serine/threonine-protein kinase GCN2 YDR283C

1 reference

Gcn1p YGL195W

1 reference

Translation elongation factor EF-1 alpha YBR118W

1 reference

author

Beatriz A Castilho

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Terri Goss Kinzy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

7

Evelyn Sattlegger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Jyothsna Visweswaraiah

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Sebastien Lageix

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Lara Izotova

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Alan G Hinnebusch

6

1 reference

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11 February 2020

language of work or name

English

0 references

publication date

17 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

11 February 2020

published in

2 references

1 December 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

36568-36579

1 reference

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11 February 2020

issue

42

1 reference

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describes a project that uses

11 February 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3196070/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3196070/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Coordination of eukaryotic translation elongation factor 1A (eEF1A) function in actin organization and translation elongation by the guanine nucleotide exchange factor eEF1Balpha

20 March 2017

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Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation

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YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed

20 March 2017

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Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells

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Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation

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Mutations in a GTP-binding motif of eukaryotic elongation factor 1A reduce both translational fidelity and the requirement for nucleotide exchange.

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Dimerization by translation initiation factor 2 kinase GCN2 is mediated by interactions in the C-terminal ribosome-binding region and the protein kinase domain

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Ribosome-binding domain of eukaryotic initiation factor-2 kinase GCN2 facilitates translation control

20 March 2017

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Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2

20 March 2017

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Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2.

20 March 2017

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PUB1 is a major nuclear and cytoplasmic polyadenylated RNA-binding protein in Saccharomyces cerevisiae

20 March 2017

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GCN20, a novel ATP binding cassette protein, and GCN1 reside in a complex that mediates activation of the eIF-2 alpha kinase GCN2 in amino acid-starved cells

20 March 2017

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GCD2, a translational repressor of the GCN4 gene, has a general function in the initiation of protein synthesis in Saccharomyces cerevisiae

20 March 2017

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Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae

20 March 2017

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Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2

20 March 2017

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29 September 2017

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29 September 2017

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Crossref

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Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111.248898

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.248898

The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

21 January 2018

1 reference

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The sulfonylurea herbicide sulfometuron methyl is an extremely potent and selective inhibitor of acetolactate synthase in Salmonella typhimurium.

27 November 2018

1 reference

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Evidence for the formation of an unusual ternary complex of rabbit liver EF-1α with GDP and deacylated tRNA

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21849502

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.248898

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21849502%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2 references

1 December 2016