(Q28066302)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

review article

2 references

5 July 2021

High Mobility Group Box-1: A Missing Link between Diabetes and Its Complications (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

complications of diabetes mellitus

27 March 2020

main subject

6 references

14 March 2019

24 March 2019

11 December 2019

19 December 2019

20 December 2019

5 July 2021

1 reference

11 December 2019

1 reference

19 December 2019

1 reference

20 December 2019

High mobility group box 1

1 reference

5 July 2021

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Lian Wang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Biao Xu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

author name string

Han Wu

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Zheng Chen

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Li-Na Kang

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

language of work or name

1 reference

25 October 2016

7 references

14 March 2019

24 March 2019

11 December 2019

19 December 2019

20 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

5 July 2021

Mediators of Inflammation

8 references

14 March 2019

24 March 2019

11 December 2019

19 December 2019

20 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

5 July 2021

2016

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

page(s)

3896147

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

27 March 2020

copyright license

6 references

14 March 2019

24 March 2019

11 December 2019

19 December 2019

20 December 2019

on focus list of Wikimedia project

5 July 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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20 March 2017

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High Mobility Group Box-1 Promotes Inflammation-Induced Lymphangiogenesis via Toll-Like Receptor 4-Dependent Signalling Pathway

29 September 2017

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29 September 2017

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HMGB1 Is Increased by CFTR Loss of Function, Is Lowered by Insulin, and Increases In Vivo at Onset of CFRD.

29 September 2017

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29 September 2017

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HMGB-1 as a Potential Target for the Treatment of Diabetic Retinopathy

29 September 2017

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The IL-1 Pathway in Type 2 Diabetes and Cardiovascular Complications.

29 September 2017

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Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction.

29 September 2017

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Plasma HMGB-1 Levels in Subjects with Obesity and Type 2 Diabetes: A Cross-Sectional Study in China

29 September 2017

1 reference

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The role of high mobility group box 1 (HMGB-1) in the diabetic retinopathy inflammation and apoptosis

29 September 2017

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HMGB1 is activated in type 2 diabetes mellitus patients and in mesangial cells in response to high glucose

29 September 2017

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Pharmacological TLR4 Inhibition Protects against Acute and Chronic Fat-Induced Insulin Resistance in Rats

29 September 2017

1 reference

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Overexpression of HMGB1 A-box reduced lipopolysaccharide-induced intestinal inflammation via HMGB1/TLR4 signaling in vitro

29 September 2017

1 reference

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The Role of HMGB1 in Cardiovascular Biology: Danger Signals

29 September 2017

1 reference

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Necrotic myocardial cells release damage-associated molecular patterns that provoke fibroblast activation in vitro and trigger myocardial inflammation and fibrosis in vivo.

29 September 2017

1 reference

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Quercetin protects necrotic insult and promotes apoptosis by attenuating the expression of RAGE and its ligand HMGB1 in human breast adenocarcinoma cells

29 September 2017

1 reference

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Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects

29 September 2017

1 reference

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HMGB1 Enhances the AGE-Induced Expression of CTGF and TGF-β via RAGE-Dependent Signaling in Renal Tubular Epithelial Cells

29 September 2017

1 reference

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High-mobility group box-1 induces vascular remodelling processes via c-Jun activation

29 September 2017

1 reference

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HMGB1 mediates hyperglycaemia-induced cardiomyocyte apoptosis via ERK/Ets-1 signalling pathway

29 September 2017

1 reference

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HMGB1 in health and disease

29 September 2017

1 reference

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Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKCβ/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1

29 September 2017

1 reference

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TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy

29 September 2017

1 reference

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The proinflammatory cytokine high-mobility group box-1 mediates retinal neuropathy induced by diabetes

29 September 2017

1 reference

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An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies.

29 September 2017

1 reference

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Role of AGEs-RAGE system in cardiovascular disease

29 September 2017

1 reference

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High-mobility group box-1 induces decreased brain-derived neurotrophic factor-mediated neuroprotection in the diabetic retina.

29 September 2017

1 reference

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Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE(-/-) mice by downregulating the HMGB1-RAGE axis

29 September 2017

1 reference

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Double-blind, randomized study evaluating the glycemic and anti-inflammatory effects of subcutaneous LY2189102, a neutralizing IL-1β antibody, in patients with type 2 diabetes

29 September 2017

1 reference

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HMGB1 is associated with atherosclerotic plaque composition and burden in patients with stable coronary artery disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Amelioration of compound 4,4'-diphenylmethane-bis(methyl)carbamate on high mobility group box1-mediated inflammation and oxidant stress responses in human umbilical vein endothelial cells via RAGE/ERK1/2/NF-κB pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

High-mobility group box-1 and endothelial cell angiogenic markers in the vitreous from patients with proliferative diabetic retinopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

High-mobility group box 1 protein is implicated in advanced glycation end products-induced vascular endothelial growth factor A production in the rat retinal ganglion cell line RGC-5.

29 September 2017

1 reference

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Novel pathways and therapies in experimental diabetic atherosclerosis

29 September 2017

1 reference

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Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy

29 September 2017

1 reference

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High-mobility group box-1 and biomarkers of inflammation in the vitreous from patients with proliferative diabetic retinopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

RAGE ligands induce apoptotic cell death of pancreatic β-cells via oxidative stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

TLR4 and Insulin Resistance

29 September 2017

1 reference

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Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Increased expression of toll-like receptor 2 in rat diabetic nephropathy

29 September 2017

1 reference

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Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects

29 September 2017

1 reference

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Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands

29 September 2017

1 reference

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Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Diabetes-Induced Oxidative Stress in Endothelial Progenitor Cells May Be Sustained by a Positive Feedback Loop Involving High Mobility Group Box-1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Modulation of HMGB1 translocation and RAGE/NFκB cascade by quercetin treatment mitigates atopic dermatitis in NC/Nga transgenic mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Ethyl pyruvate inhibits retinal pathogenic neovascularization by downregulating HMGB1 expression

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Osteopontin and other regulators of angiogenesis and fibrogenesis in the vitreous from patients with proliferative vitreoretinal disorders

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Heat shock transcription factor 1 inhibits H₂O₂-induced cardiomyocyte death through suppression of high-mobility group box 1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

A New Group of Chromatin-Associated Proteins with a High Content of Acidic and Basic Amino Acids

2 June 2018

1 reference

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Toll-like receptor 4/spleen tyrosine kinase complex in high glucose signal transduction of proximal tubular epithelial cells

2 June 2018

1 reference

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IFN-γ-producing Th17 cells bias by HMGB1-T-bet/RUNX3 axis might contribute to progression of coronary artery atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Islet-associated macrophages in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

One week treatment with the IL-1 receptor antagonist anakinra leads to a sustained improvement in insulin sensitivity in insulin resistant patients with type 1 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Insulin infusion suppresses while glucose infusion induces Toll-like receptors and high-mobility group-B1 protein expression in mononuclear cells of type 1 diabetes patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Involvement of HMGB1 mediated signalling pathway in diabetic retinopathy: evidence from type 2 diabetic rats and ARPE-19 cells under diabetic condition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

High mobility group box 1 (HMGB1) mediates high-glucose-induced calcification in vascular smooth muscle cells of saphenous veins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Inhibition of high-mobility group box 1 improves myocardial fibrosis and dysfunction in diabetic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Metformin protects against hyperglycemia-induced cardiomyocytes injury by inhibiting the expressions of receptor for advanced glycation end products and high mobility group box 1 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Expression of high-mobility group box protein 1 in diabetic foot atherogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

HMGB1: the missing link between diabetes mellitus and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

High-Mobility Group Box-1 Modulates the Expression of Inflammatory and Angiogenic Signaling Pathways in Diabetic Retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

High-mobility group box-1 protein activates inflammatory signaling pathway components and disrupts retinal vascular-barrier in the diabetic retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Mutual enhancement between high-mobility group box-1 and NADPH oxidase-derived reactive oxygen species mediates diabetes-induced upregulation of retinal apoptotic markers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Circulating high-mobility group box 1 and cardiovascular mortality in unstable angina and non-ST-segment elevation myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Global Toll-like receptor 4 knockout results in decreased renal inflammation, fibrosis and podocytopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

High-Mobility Group Box-1 Protein Mediates the Regulation of Signal Transducer and Activator of Transcription-3 in the Diabetic Retina and in Human Retinal Müller Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Perineural expression of high-mobility group box-1 contributes to long-lasting mechanical hypersensitivity via matrix metalloproteinase-9 upregulation in mice with painful peripheral neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Astilbin protects diabetic rat heart against ischemia-reperfusion injury via blockade of HMGB1-dependent NF-κB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-kappaB expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Relationship of Soluble RAGE and RAGE Ligands HMGB1 and EN-RAGE to Endothelial Dysfunction in Type 1 and Type 2 Diabetes Mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3896147

Prognostic value of the high-mobility group box-1 in young patients with chest pain

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

IL-1 receptor deficiency slows progression to diabetes in the NOD mouse

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5099456

The isolation and purification of the high mobility group (HMG) nonhistone chromosomal proteins

27 November 2018

1 reference

12 December 2020

HMGB1 signals danger in acute coronary syndrome: emergence of a new risk marker for cardiovascular death?

1 reference

12 December 2020

High-mobility group box 1 protein promotes development of microvascular thrombosis in rats

1 reference

12 December 2020

Serum IL-1, IL-2, TNFalpha and INFgamma levels of patients with type 1 diabetes mellitus and their siblings

1 reference

12 December 2020

Paucity of CD34-positive cells and increased expression of high-mobility group box 1 in coronary thrombus with type 2 diabetes mellitus

1 reference

12 December 2020

Increased serum HMGB1 related with HbA1c in coronary artery disease with type 2 diabetes mellitus

1 reference

12 December 2020

Alarmin high-mobility group B1 (HMGB1) is regulated in human adipocytes in insulin resistance and influences insulin secretion in β-cells

1 reference

12 December 2020

Increased serum HMGB1 level is associated with coronary artery disease in nondiabetic and type 2 diabetic patients.

1 reference

12 December 2020

The role of high-mobility group box-1 protein in the development of diabetic nephropathy

1 reference

12 December 2020

Increased serum high-mobility group box-1 and cleaved receptor for advanced glycation endproducts levels and decreased endogenous secretory receptor for advanced glycation endproducts levels in diabetic and non-diabetic patients with heart failure

1 reference

12 December 2020

Identifiers

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27847406%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

2 references