(Q38593252)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

1 reference

Sattar Gorgani-Firuzjaee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Ghodratollah Panahi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

author name string

Hadi Khodabandehloo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Reza Meshkani

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

language of work or name

1 reference

5 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

published in

Translational Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

volume

167

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

page(s)

228-256

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26408801%20AND%20SRC:MED&resulttype=core&format=json

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

25 February 2020

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

7 January 2021

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Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

7 January 2021

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Elevated C-reactive protein levels in overweight and obese adults

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Adipose tissues as an ancestral immune organ: site-specific change in obesity.

1 reference

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Adipose tissue as a dedicated reservoir of functional mast cell progenitors.

7 January 2021

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7 January 2021

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Macrophages, inflammation, and insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The secretory function of adipocytes in the physiology of white adipose tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Obesity-associated mouse adipose stem cell secretion of monocyte chemotactic protein-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Obesity is associated with macrophage accumulation in adipose tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The chemokine system in diverse forms of macrophage activation and polarization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbid obese subjects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

7 January 2021

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Diet induction of monocyte chemoattractant protein-1 and its impact on obesity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Gene profiling of human adipose tissue during evoked inflammation in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Fractalkine is a novel human adipochemokine associated with type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Leukocyte influx in atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Normalization of obesity-associated insulin resistance through immunotherapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Mast cell content and fatty acid metabolism in the epididymal fat pad of obese mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Activation of human inflammatory cells by secreted phospholipases A2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

High frequency of activated natural killer and natural killer T-cells in patients with new onset of type 2 diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Influence of obesity on immune function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Are natural killer cells protecting the metabolically healthy obese patient?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

NK cells: immune cross-talk and therapeutic implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The role of innate immune cells in obese adipose tissue inflammation and development of insulin resistance.

7 January 2021

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Regulation of steady-state neutrophil homeostasis by macrophages.

7 January 2021

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Leukocytosis in obese individuals: possible link in patients with unexplained persistent neutrophilia

7 January 2021

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Body fat and circulating leukocytes in children

7 January 2021

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Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding

7 January 2021

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Obesity and immune function relationships.

7 January 2021

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Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin

7 January 2021

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Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease

7 January 2021

1 reference

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Adipocyte-selective reduction of the leptin receptors induced by antisense RNA leads to increased adiposity, dyslipidemia, and insulin resistance

7 January 2021

1 reference

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Adipocytokines: leptin--the classical, resistin--the controversical, adiponectin--the promising, and more to come

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Adipocytokines: mediators linking adipose tissue, inflammation and immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Plasma adiponectin and leptin levels, body composition, and glucose utilization in adult women with wide ranges of age and obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Adiponectin is associated with serum and adipose tissue fatty acid composition in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Metabolic inflammation: connecting obesity and insulin resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Signal integration in the endoplasmic reticulum unfolded protein response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Molecular inflammation: underpinnings of aging and age-related diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Hypoxia and adipose tissue function and dysfunction in obesity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease

7 January 2021

1 reference

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Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Toll-like receptors in the pathogenesis of human disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

7 January 2021

1 reference

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Pathogen recognition by innate receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Interactions of Toll-like receptors with fungi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Current views of toll-like receptor signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Innate immune recognition of viral infection

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Toll-like receptors: linking inflammation to metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance

7 January 2021

1 reference

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Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat.

7 January 2021

1 reference

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Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Missing pieces in the NF-kappaB puzzle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Selective interaction of JNK protein kinase isoforms with transcription factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Prevention of fat-induced insulin resistance by salicylate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Salsalate improves glycemia and inflammatory parameters in obese young adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Activation of the JNK-AP-1 signal transduction pathway is associated with pathogenesis and progression of human osteosarcomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The regulation of AP-1 activity by mitogen-activated protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Hepatitis C Virus Infection Induces Apoptosis through a Bax-Triggered, Mitochondrion-Mediated, Caspase 3-Dependent Pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

West Nile Virus Infection Activates the Unfolded Protein Response, Leading to CHOP Induction and Apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

ER stress and the unfolded protein response in intestinal inflammation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

ER Stress and Lipid Metabolism in Adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβ and mTOR-dependent dephosphorylation of Akt.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Intracellular NOD-like receptors in host defense and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Molecular mechanisms involved in inflammasome activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The NLRP3 Inflammasome as a novel player of the intercellular crosstalk in metabolic disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Tumour necrosis factor alpha is pro-inflammatory in normal human skin and modulates cutaneous adhesion molecule expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

TNF-R1 signaling: a beautiful pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Immunological and inflammatory functions of the interleukin-1 family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Mature-Onset Obesity in Interleukin-1 Receptor I Knockout Mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Adipose tissue is a major source of interleukin-1 receptor antagonist: upregulation in obesity and inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Interleukin (IL)-6 mRNA Expression is Stimulated by Insulin, Isoproterenol, Tumour Necrosis Factor Alpha, Growth Hormone, and IL-6 in 3T3-L1 Adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Acute hyperinsulinemia raises plasma interleukin-6 in both nondiabetic and type 2 diabetes mellitus subjects, and this effect is inversely associated with body mass index

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Muscle as an endocrine organ: focus on muscle-derived interleukin-6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Pathophysiology of insulin resistance in human disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The relationship between homeostasis model assessment and cardiovascular risk factors in Iranian subjects with normal fasting glucose and normal glucose tolerance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Hepatic insulin resistance, metabolic syndrome and cardiovascular disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The TOR kinases link nutrient sensing to cell growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Molecular mechanisms of mTOR-mediated translational control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Corneal endothelium evaluation in type I and type II diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Impact of mitochondrial ROS production in the pathogenesis of diabetes mellitus and its complications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

PKC-theta knockout mice are protected from fat-induced insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

TNF-alpha induces mitochondrial dysfunction in 3T3-L1 adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Inflammation and metabolic disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Mitogen-activated protein kinases, inhibitory-kappaB kinase, and insulin signaling in human omental versus subcutaneous adipose tissue in obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Obesity, Inflammation, and Insulin Resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

IKK-beta links inflammation to obesity-induced insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

A central role for JNK in obesity and insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Mitochondrial respiratory-chain diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein kinase C isoforms: mediators of reactive lipid metabolites in the development of insulin resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Specific protein kinase C isoforms as transducers and modulators of insulin signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Cytokine regulation of skeletal muscle fatty acid metabolism: effect of interleukin-6 and tumor necrosis factor-alpha.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Differential effects of tumor necrosis factor-alpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin receptor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

SOCS proteins causing trouble in insulin action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Constitutive expression of suppressor of cytokine signalling-3 in skeletal muscle leads to reduced mobility and overweight in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Cytokines modulate glucose transport in skeletal muscle by inducing the expression of inducible nitric oxide synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein tyrosine phosphatase 1B inhibition ameliorates palmitate-induced mitochondrial dysfunction and apoptosis in skeletal muscle cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein tyrosine phosphatase 1B (PTP1B) modulates palmitate-induced cytokine production in macrophage cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Palmitate-induced PTP1B expression is mediated by ceramide-JNK and nuclear factor κB (NF-κB) activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein tyrosine phosphatase-1B (PTP-1B) knockdown improves palmitate-induced insulin resistance in C2C12 skeletal muscle cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Palmitate and inflammatory state additively induce the expression of PTP1B in muscle cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Palmitate enhances protein tyrosine phosphatase 1B (PTP1B) gene expression at transcriptional level in C2C12 skeletal muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Leukocyte antigen-related inhibition attenuates palmitate-induced insulin resistance in muscle cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5'-phosphatase 2) on insulin signaling and glucose metabolism in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The lipid phosphatase SHIP2 controls insulin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Palmitate induces SHIP2 expression via the ceramide-mediated activation of NF-κB, and JNK in skeletal muscle cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Inhibition of SH2-domain-containing inositol 5-phosphatase (SHIP2) ameliorates palmitate induced-apoptosis through regulating Akt/FOXO1 pathway and ROS production in HepG2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Okadaic acid activates atypical protein kinase C (zeta/lambda) in rat and 3T3/L1 adipocytes. An apparent requirement for activation of Glut4 translocation and glucose transport

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Altered regulation of insulin signaling components in adipocytes of insulin-resistant type II diabetic Goto-Kakizaki rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Effect of tumor necrosis factor-alpha on insulin-stimulated mitogen-activated protein kinase cascade in cultured rat skeletal muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Transcriptional and translational regulation of cytokine signaling in inflammatory β-cell dysfunction and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Gastric bypass and banding equally improve insulin sensitivity and β cell function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Immunology in the Clinic Review Series; focus on metabolic diseases: development of islet autoimmune disease in type 2 diabetes patients: potential sequelae of chronic inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The use of interleukin-1-receptor antagonists in the treatment of diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Increased number of islet-associated macrophages in type 2 diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Macrophages and islet inflammation in type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The heterogeneity of diabetes: unraveling a dispute: is systemic inflammation related to islet autoimmunity?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

The Fas pathway is involved in pancreatic beta cell secretory function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Diabetes and beta cell function: from mechanisms to evaluation and clinical implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Metabolic stress, IAPP and islet amyloid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Islet inflammation: a unifying target for diabetes treatment?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Cytokine production by islets in health and diabetes: cellular origin, regulation and function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Inflammation and type one diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Type 2 diabetes as an inflammatory disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Assessing progression to impaired glucose tolerance and type 2 diabetes mellitus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Insulin resistance and impaired insulin secretion in subjects with histories of gestational diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Insulin secretion and insulin sensitivity at different stages of glucose tolerance: a cross-sectional study of Japanese type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Insulin-secretion capacity in normal glucose tolerance, impaired glucose tolerance, and diabetes in obese and non-obese Japanese patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

β cell dysfunction versus insulin resistance in the pathogenesis of type 2 diabetes in East Asians

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Skeletal muscle insulin resistance is the primary defect in type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Beta cell dysfunction and insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Diabetes mellitus and the β cell: the last ten years

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Pathomechanisms of type 2 diabetes genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011

Television viewing habits associated with obesity risk factors: a survey of Melbourne schoolchildren

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.08.011