(Q28068353)

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Potential Links between Impaired One-Carbon Metabolism Due to Polymorphisms, Inadequate B-Vitamin Status, and the Development of Alzheimer's Disease

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Potential Links between Impaired One-Carbon Metabolism Due to Polymorphisms, Inadequate B-Vitamin Status, and the Development of Alzheimer's Disease (English)

1 reference

Alzheimer's disease

12 references

14 March 2019

19 March 2019

24 March 2019

22 April 2019

25 April 2019

19 June 2019

30 June 2019

14 September 2019

19 September 2019

19 November 2019

based on heuristic

inferred from title

2 October 2020

hyperhomocysteinemia

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14 March 2019

19 March 2019

24 March 2019

22 April 2019

25 April 2019

19 June 2019

30 June 2019

14 September 2019

19 September 2019

19 November 2019

2 October 2020

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genetic variation

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14 September 2019

biomedical investigative technique

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19 September 2019

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19 November 2019

evidence-based medicine

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2 October 2020

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2 October 2020

Barbara Troesch

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7 June 2020

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Peter Weber

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M Hasan Mohajeri

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10 December 2016

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30 June 2019

14 September 2019

19 September 2019

19 November 2019

2 October 2020

12 references

14 March 2019

19 March 2019

24 March 2019

22 April 2019

25 April 2019

19 June 2019

30 June 2019

14 September 2019

19 September 2019

19 November 2019

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27973419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

2 October 2020

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Homocysteine and vascular disease: review of published results of the homocysteine-lowering trials

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Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase

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Inadequate supply of vitamins and DHA in the elderly: implications for brain aging and Alzheimer-type dementia

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Neuropathological alterations in Alzheimer disease

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The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia

1 reference

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20 March 2017

Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA Bank.

1 reference

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Methionine synthase polymorphism is a risk factor for Alzheimer disease

1 reference

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Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

20 March 2017

Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase

1 reference

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Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein

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Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction

1 reference

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A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida

1 reference

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Methionine synthase reductase 66A->G polymorphism is associated with increased plasma homocysteine concentration when combined with the homozygous methylenetetrahydrofolate reductase 677C->T variant

1 reference

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Does disturbed homocysteine and folate metabolism in depression result from enhanced oxidative stress?

1 reference

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20 March 2017

Phosphatidylethanolamine N-methyltransferase from liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

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Structure-based perspectives on B12-dependent enzymes

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Human methionine synthase. cDNA cloning, gene localization, and expression

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Komrower Lecture. Molecular basis of phenotype expression in homocystinuria

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Molecular basis of cystathionine beta-synthase deficiency in pyridoxine responsive and nonresponsive homocystinuria

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The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations

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B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice

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Public health significance of elevated homocysteine

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Age-specific epigenetic drift in late-onset Alzheimer's disease

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gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells.

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Oxidative DNA damage and level of thiols as related to polymorphisms of MTHFR, MTR, MTHFD1 in Alzheimer's and Parkinson's diseases

1 reference

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The methylenetetrahydrofolate reductase 677C-->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism

1 reference

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29 September 2017

Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation.

1 reference

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Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial

1 reference

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Differences in risk factors for dementia with neurodegenerative traits and for vascular dementia.

1 reference

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Amyloid beta-peptide(1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain

1 reference

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Association of IL-1 RN*2 allele and methionine synthase 2756 AA genotype with dementia severity of sporadic Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Methylenetetrahydrofolate reductase (MTHFR) c677t gene variant modulates the homocysteine folate correlation in a mild folate-deficient population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Current concepts in cobalamin deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Homocysteine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

High prevalence of a mutation in the cystathionine beta-synthase gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (> or = 40 micromol/liter). The Hordaland Homocysteine Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Methylation reactions in the formation and metabolism of catecholamines and other biogenic amines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Chemical and nutritional aspects of folate research: analytical procedures, methods of folate synthesis, stability, and bioavailability of dietary folates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

29 September 2017

Analysis of methionine synthase reductase polymorphism (A66G) in Indian Muslim population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Alzheimer's disease: development of disease-modifying treatments is the challenge for our generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Meta-analysis of the methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Hyperhomocysteinemia increases beta-amyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

A common polymorphism in methionine synthase reductase increases risk of premature coronary artery disease.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

ACE, MTHFR, factor V Leiden, and APOE polymorphisms in patients with vascular and Alzheimer's dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Methionine synthase and neural tube defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Biological methylation of myelin basic protein: enzymology and biological significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Betaine-homocysteine methyltransferase: organ distribution in man, pig and rat and subcellular distribution in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

2 June 2018

Alzheimer's researchers call for clinical revamp.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Folate, homocysteine, vitamin B12, and polymorphisms of genes participating in one-carbon metabolism in late-onset Alzheimer's disease patients and healthy controls

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

A metabolic link between S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

A 31 bp VNTR in the cystathionine beta-synthase (CBS) gene is associated with reduced CBS activity and elevated post-load homocysteine levels

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Assessing the association between homocysteine and cognition: reflections on Bradford Hill, meta-analyses, and causality.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

B-vitamins reduce plasma levels of beta amyloid

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Folate-mediated one-carbon metabolism

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Identification of six methylenetetrahydrofolate reductase (MTHFR) genotypes resulting from common polymorphisms: impact on plasma homocysteine levels and development of coronary artery disease.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Polygenic influence on plasma homocysteine: association of two prevalent mutations, the 844ins68 of cystathionine beta-synthase and A(2756)G of methionine synthase, with lowered plasma homocysteine levels.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Methylenetetrahydrofolate reductase gene and risk of Alzheimer's disease in Koreans

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

5,10-Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms: genotype frequency and association with homocysteine and folate levels in middle-southern Italian adults

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Genetic defects as important factors for moderate hyperhomocysteinemia

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Riboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C->T polymorphism

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Polymorphism of the methionine synthase gene : association with homocysteine metabolism and late-onset vascular diseases in the Japanese population

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Genetic causes of mild hyperhomocysteinemia in patients with premature occlusive coronary artery diseases.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Functional vitamin B(12) deficiency and Alzheimer disease

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas; a report of a novel MTHFR polymorphic site, G1793A.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

MTRR and MTHFR polymorphism: link to Down syndrome?

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Molecular basis of phenotype expression in homocystinuria

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Novel alleles of 31-bp VNTR polymorphism in the human cystathionine β-synthase (CBS) gene were detected in healthy Asians

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Lack of genetic dispositions to hyperhomocysteinemia in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

The C677T methylenetetrahydrofolate reductase mutation is not associated with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Plasma folate, vitamin B(12), and total homocysteine and homozygosity for the C677T mutation of the 5,10-methylene tetrahydrofolate reductase gene in patients with Alzheimer's dementia. A case-control study.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Methylenetetrahydrofolate reductase and angiotensin converting enzyme gene polymorphisms in two genetically and diagnostically distinct cohort of Alzheimer patients

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Is MTHFR polymorphism a risk factor for Alzheimer's disease like APOE?

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

C677T methylentetrahydrofulate reductase and angiotensin converting enzyme gene polymorphisms in patients with Alzheimer's disease in Iranian population.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Plasma total homocysteine levels and the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene: a study in an Italian population with dementia.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Abeta peptides as one of the crucial volume transmission signals in the trophic units and their interactions with homocysteine. Physiological implications and relevance for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake?

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Folate deficiency and over-supplementation causes impaired folate metabolism: Regulation and adaptation mechanisms in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Folate quenches oxidative damage in brains of apolipoprotein E-deficient mice: augmentation by vitamin E.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

A haplotype of the methylenetetrahydrofolate reductase gene is protective against late-onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

The role of the polymorphic genes apolipoprotein E and methylene- tetrahydrofolate reductase in the development of dementia of the Alzheimer type.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Comparison of prevalence of inadequate nutrient intake based on body weight status of adults in the United States: an analysis of NHANES 2001-2008.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Impact of voluntary fortification and supplement use on dietary intakes and biomarker status of folate and vitamin B-12 in Irish adults.

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Improvement of cognitive functions after cobalamin/folate supplementation in elderly patients with dementia and elevated plasma homocysteine

1 reference

https://api.crossref.org/works/10.3390%2FNU8120803

21 January 2018

Hyperhomocysteinemia in Alzheimer's disease: the hen and the egg?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

Association between genetic and environmental factors and the risk of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

Phosphatidylethanolamine-N-methyltransferase Activity and Dietary Choline Regulate Liver-Plasma Lipid Flux and Essential Fatty Acid Metabolism in Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

5,10-methylenetetrahydrofolate reductase common mutations, folate status and plasma homocysteine in healthy French adults of the Supplementation en Vitamines et Mineraux Antioxydants (SU.VI.MAX) cohort.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

The role of vitamin B12 in fasting hyperhomocysteinemia and its interaction with the homozygous C677T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene. A case-control study of patients with early-onset thrombotic events.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5188458

27 November 2018

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common mutation A1298C in human methylenetetrahydrofolate reductase gene: association with plasma total homocysteine and folate concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic methylation of the membrane-bound nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase mutation (677C-->T) negatively influences plasma homocysteine response to marginal folate intake in elderly women

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress is associated with genetic polymorphisms in one-carbon metabolism in coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homocysteine and risk of premature coronary heart disease. Evidence for a common gene mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptosomal plasma membrane transport of excitatory sulphur amino acid transmitter candidates: kinetic characterisation and analysis of carrier specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of heterozygosity for the methionine synthase 2756 A-->G mutation on the risk for recurrent cardiovascular events

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin B-12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of MTHFR C677T with total homocysteine plasma levels and susceptibility to Parkinson's disease: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage disequilibrium at the cystathionine β synthase (CBS) locus and the association between genetic variation at the CBS locus and plasma levels of homocysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for heme-mediated redox regulation of human cystathionine beta-synthase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinaemia in neural-tube defects and vascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common 844INS68 insertion variant in the cystathionine beta-synthase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Labile methyl balances for normal humans on various dietary regimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/27973419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/NU8120803

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27973419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27973419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

2 references

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27973419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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