(Q28143960)

1

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M Maratrat

2

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V Sierra

3

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E Conseiller

4

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L Debussche

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

5

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language of work or name

English

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publication date

8 April 1999

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published in

Oncogene

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volume

18

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page(s)

2405-10

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issue

14

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53 in signaling checkpoint arrest or apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Two tandem and independent sub-activation domains in the amino terminus of p53 require the adaptor complex for activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

CTS1: a p53-derived chimeric tumor suppressor gene with enhanced in vitro apoptotic properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Critical structural elements of the VP16 transcriptional activation domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Definition of a consensus binding site for p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

A transcriptionally active DNA-binding site for human p53 protein complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53 in growth control and neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53; from inductive signal to cellular effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Wild-type p53 negatively regulates the expression of a microtubule-associated protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021

Identification of a novel p53 functional domain that is necessary for mediating apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202539

7 January 2021