(Q28188852)

3

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author name string

S Yamasaki

1

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K Nishida

2

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M Sakuma

4

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R Shiina

5

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H Ohnishi

7

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T Hirano

8

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T Saito

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

30 November 2001

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published in

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volume

276

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page(s)

45175-83

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issue

48

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cites work

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Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory signal through the membrane-proximal region in the absence of the tyrosine motif in the cytoplasmic tail

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Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

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G proteins in lymphocyte signalling

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T cell activation and the cytoskeleton

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Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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Integration of T cell receptor-dependent signaling pathways by adapter proteins

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From form to function: signaling by protein tyrosine phosphatases.

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Shp-2 tyrosine phosphatase: signaling one cell or many

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The phosphotyrosine phosphatase SHP-2 participates in a multimeric signaling complex and regulates T cell receptor (TCR) coupling to the Ras/mitogen-activated protein kinase (MAPK) pathway in Jurkat T cells

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Molecular basis of T cell inactivation by CTLA-4

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Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck).

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PD-L2 is a second ligand for PD-1 and inhibits T cell activation

21 January 2018

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Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

21 January 2018

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A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

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Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

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Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

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Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

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Engagement of Gab1 and Gab2 in erythropoietin signaling

21 January 2018

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Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

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Inhibition of the T-cell receptor-mediated signal transduction by microinjection of anti-Lck monoclonal antibody into T-cells

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New experimental approaches in retrovirus-mediated expression screening

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Efficient retroviral-mediated gene transfer into human B lymphoblastoid cells expressing mouse ecotropic viral receptor

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Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling

21 January 2018

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Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

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Signal transduction mediated by the T-cell antigen receptor

21 January 2018

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Essential role of LAT in T cell development

21 January 2018

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Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2

21 January 2018

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A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes

21 January 2018

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The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.

21 January 2018

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Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

21 January 2018

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Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M105384200

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105384200

The Gab1 docking protein links the b cell antigen receptor to the phosphatidylinositol 3-kinase/Akt signaling pathway and to the SHP2 tyrosine phosphatase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105384200

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105384200

The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization

21 January 2018

1 reference

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Crystal structure of the tyrosine phosphatase SHP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105384200

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M105384200

Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

21 January 2018

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FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation

21 January 2018

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Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling

21 January 2018

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Negative regulation of cytokine signaling pathways

21 January 2018

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Human Influence on the Atmospheric Vertical Temperature Structure: Detection and Observations

21 January 2018

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