(Q28208861)

1

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Zeb Khan

2

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David W Coomber

3

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David P Lane

4

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Maureen Higgins

5

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Maria M Koufali

6

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Sonia Lain

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

23 May 2003

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published in

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volume

278

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issue

21

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page(s)

18720-9

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cites work

Live or let die: the cell's response to p53

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

The blood-brain barrier and cerebral angiogenesis: lessons from the cold-injury model

21 January 2018

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211007200

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211007200

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

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An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

21 January 2018

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Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.

21 January 2018

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Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211007200

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211007200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

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Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

ARF function does not require p53 stabilization or Mdm2 relocalization

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

p53-independent functions of the p19(ARF) tumor suppressor

21 January 2018

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The INK4a/ARF network in tumour suppression

21 January 2018

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The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

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Mapping of the p53 and mdm-2 interaction domains

21 January 2018

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Characterisation of epitopes on human p53 using phage-displayed peptide libraries: insights into antibody-peptide interactions.

21 January 2018

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Directed proteomic analysis of the human nucleolus

21 January 2018

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An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs

21 January 2018

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Sedimentation analyses of the salt- and divalent metal ion-induced oligomerization of nucleolar protein B23

21 January 2018

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Defining the molecular basis of Arf and Hdm2 interactions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

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Oxidants, oxidative stress and the biology of ageing

21 January 2018

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Nucleophosmin regulates the stability and transcriptional activity of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

Solution structure of the p53 regulatory domain of the p19Arf tumor suppressor protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

Identification of a cryptic nucleolar-localization signal in MDM2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211007200

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211007200

Cloning, sequence analysis and expression of the cDNAs encoding the canine and equine homologues of the mouse double minute 2 (mdm2) proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211007200