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MdmX inhibits Smad transactivation
scientific article (publication date: 12 December 2002)
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instance of
scholarly article
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title
MdmX inhibits Smad transactivation
(English)
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author name string
Madhavi Kadakia
series ordinal
1
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Thomas L Brown
series ordinal
2
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Molly M McGorry
series ordinal
3
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Steven J Berberich
series ordinal
4
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language of work or name
English
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publication date
12 December 2002
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published in
Oncogene
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volume
21
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issue
57
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page(s)
8776-85
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cites work
Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
21 January 2018
c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different sensitivity of the transforming growth factor-beta cell cycle arrest pathway to c-Myc and MDM-2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Smads: transcriptional regulation and mouse models
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of p21 cannot substitute for p53 loss in rescue of mdm2 null lethality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smads: transcriptional activators of TGF-beta responses
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
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inferred from DOI database lookup
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p300 and CBP: partners for life and death
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p300/MDM2 complexes participate in MDM2-mediated p53 degradation
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive mdmx expression during cell growth, differentiation, and DNA damage
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stated in
Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MdmX protects p53 from Mdm2-mediated degradation
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p63 function by Mdm2 and MdmX.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGFbeta signaling in growth control, cancer, and heritable disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity, diversity, and regulation in TGF-beta superfamily signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical and functional interaction of SMADs and p300/CBP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-independent role of MDM2 in TGF-beta1 resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2 interacts with MDMX through their RING finger domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta 1 induces differentiation-specific gene expression in fetal rat brown adipocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Smad activity
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Smad pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 mutant defective in binding p300 promotes ubiquitination but not degradation of p53: evidence for the role of p300 in integrating ubiquitination and proteolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205993
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1205993
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3178982
Dimensions Publication ID
1022948054
0 references
OpenCitations bibliographic resource ID
3178982
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3178982
PubMed ID
12483531
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3178982
ResearchGate publication ID
10988827
0 references
Springer Nature article ID
10.1038/sj.onc.1205993
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