(Q28236097)

23 March 2017

author name string

George R Stark

1

0 references

William R Taylor

2

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George R. Stark

1

1 reference

23 March 2017

William R. Taylor

2

1 reference

23 March 2017

language of work or name

English

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publication date

March 2006

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2006

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23 March 2017

published in

Molecular Biotechnology

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23 March 2017

volume

32

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23 March 2017

issue

3

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23 March 2017

page(s)

227-48

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227-248

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p21 Inhibits Thr161Phosphorylation of Cdc2 to Enforce the G2DNA Damage Checkpoint

23 March 2017

cites work

1 reference

12 December 2020

Polo-like kinase-1 is a target of the DNA damage checkpoint

1 reference

12 December 2020

Cell cycle checkpoints: preventing an identity crisis

1 reference

12 December 2020

Intra-M phase-promoting factor phosphorylation of cyclin B at the prophase/metaphase transition.

1 reference

12 December 2020

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

12 December 2020

Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins

1 reference

12 December 2020

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

1 reference

12 December 2020

Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor

1 reference

12 December 2020

Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

12 December 2020

Questioning the role of checkpoint kinase 2 in the p53 DNA damage response

1 reference

12 December 2020

Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes

1 reference

12 December 2020

The G2-phase DNA-damage checkpoint

1 reference

12 December 2020

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

1 reference

12 December 2020

p53 regulates a G2 checkpoint through cyclin B1

1 reference

12 December 2020

Centrosomal and cytoplasmic Cdc2/cyclin B1 activation precedes nuclear mitotic events

1 reference

12 December 2020

Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1 reference

12 December 2020

Functionally homologous cell cycle control genes in budding and fission yeast

1 reference

12 December 2020

Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation

1 reference

12 December 2020

Genetic control of cell size at cell division in yeast

1 reference

12 December 2020

T antigen is bound to a host protein in SY40-transformed cells

1 reference

12 December 2020

E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes

1 reference

12 December 2020

The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1

1 reference

12 December 2020

Oncogenic intelligence: Cell immortalization and transformation by the p53 gene

1 reference

12 December 2020

Cooperative effects of genes controlling the G(2)/M checkpoint

1 reference

12 December 2020

Cyclic activation of histone H1 kinase during sea urchin egg mitotic divisions

1 reference

12 December 2020

Two cellular proteins that bind to wild-type but not mutant p53

1 reference

12 December 2020

A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease

1 reference

12 December 2020

Ran-independent nuclear import of cyclin B1-Cdc2 by importin beta

1 reference

12 December 2020

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

1 reference

12 December 2020

Mechanisms of G2 arrest in response to overexpression of p53

1 reference

12 December 2020

G1/S-regulated E2F-containing protein complexes bind to the mouse thymidine kinase gene promoter.

1 reference

12 December 2020

The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues

1 reference

12 December 2020

S-phase feedback control in budding yeast independent of tyrosine phosphorylation of P34cdc28

1 reference

12 December 2020

E2F mediates sustained G2 arrest and down-regulation of Stathmin and AIM-1 expression in response to genotoxic stress

1 reference

12 December 2020

Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1

1 reference

12 December 2020

The Chk2 tumor suppressor is not required for p53 responses in human cancer cells

1 reference

12 December 2020

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

12 December 2020

Purification and characterization of human DNA damage checkpoint Rad complexes

1 reference

12 December 2020

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

1 reference

12 December 2020

Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

1 reference

12 December 2020

Purification of maturation-promoting factor, an intracellular regulator of early mitotic events

1 reference

12 December 2020

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

12 December 2020

A kinase from fission yeast responsible for blocking mitosis in S phase

1 reference

12 December 2020

F1-histone modification at metaphase in Chinese hamster cells.

1 reference

12 December 2020

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1 reference

12 December 2020

Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control

1 reference

12 December 2020

Cyclin is a component of maturation-promoting factor from Xenopus

1 reference

12 December 2020

MDM2--master regulator of the p53 tumor suppressor protein

1 reference

12 December 2020

Identification of a cell-type-specific and E2F-independent mechanism for repression of cdc2 transcription

1 reference

12 December 2020

p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases

1 reference

12 December 2020

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

1 reference

12 December 2020

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

1 reference

12 December 2020

GADD45 induction of a G2/M cell cycle checkpoint

1 reference

12 December 2020

Induction of nuclear envelope breakdown, chromosome condensation, and spindle formation in cell-free extracts

1 reference

12 December 2020

Cyclins and cyclin-dependent kinases: a biochemical view

1 reference

12 December 2020

Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair

1 reference

12 December 2020

Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts.

1 reference

12 December 2020

Inhibition of cyclin-dependent kinases by p21

1 reference

12 December 2020

Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation

1 reference

12 December 2020

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

12 December 2020

p53 regulation of G(2) checkpoint is retinoblastoma protein dependent

1 reference

12 December 2020

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1 reference

12 December 2020

Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+

1 reference

12 December 2020

Sibling rivalry in the E2F family

1 reference

12 December 2020

Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases

1 reference

12 December 2020

Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF

1 reference

12 December 2020

Sensing and responding to DNA damage.

1 reference

12 December 2020

Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1.

1 reference

12 December 2020

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

1 reference

12 December 2020

Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae

1 reference

12 December 2020

53BP1, a mediator of the DNA damage checkpoint

1 reference

12 December 2020

Caffeine inhibits the checkpoint kinase ATM

1 reference

12 December 2020

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

1 reference

12 December 2020

Ionizing radiation induces rapid tyrosine phosphorylation of p34cdc2

1 reference

12 December 2020

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

1 reference

12 December 2020

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1 reference

12 December 2020

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

12 December 2020

BRCA1 mutations in primary breast and ovarian carcinomas

1 reference

12 December 2020

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

12 December 2020

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

12 December 2020

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

12 December 2020

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

1 reference

12 December 2020

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1 reference

12 December 2020

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

1 reference

12 December 2020

A novel Rad24 checkpoint protein complex closely related to replication factor C.

1 reference

12 December 2020

Cyclin synthesis drives the early embryonic cell cycle

1 reference

12 December 2020

Checking out the G(2)/M transition.

1 reference

12 December 2020

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

1 reference

12 December 2020

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

1 reference

12 December 2020

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

12 December 2020

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

12 December 2020

Coupling of mitosis to the completion of S phase through Cdc34-mediated degradation of Wee1.

1 reference

12 December 2020

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

1 reference

12 December 2020

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

1 reference

12 December 2020

p130/E2F4 binds to and represses the cdc2 promoter in response to p53.

1 reference

12 December 2020

Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase

1 reference

12 December 2020

Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression

1 reference

12 December 2020

Requirement of the MRN complex for ATM activation by DNA damage

1 reference

12 December 2020

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

1 reference

12 December 2020

A genetic model for colorectal tumorigenesis

1 reference

12 December 2020

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

1 reference

12 December 2020

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation.

1 reference

12 December 2020

p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2.

1 reference

12 December 2020

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

1 reference

12 December 2020

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

1 reference

12 December 2020

Checkpoints: controls that ensure the order of cell cycle events

1 reference

12 December 2020

Inhibition of p34cdc2 kinase activity by etoposide or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells

1 reference

12 December 2020

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

1 reference

12 December 2020

MPF localization is controlled by nuclear export

1 reference

12 December 2020

Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint

1 reference

12 December 2020

Control of Cell Division by Very Lysine Rich Histone (F1) Phosphorylation

1 reference

12 December 2020

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

1 reference

12 December 2020

Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression

1 reference

12 December 2020

The retinoblastoma gene family in differentiation and development.

1 reference

12 December 2020

DNA damage activates p53 through a phosphorylation-acetylation cascade

1 reference

12 December 2020

cdc2 is a component of the M phase-specific histone H1 kinase: evidence for identity with MPF

1 reference

12 December 2020

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

1 reference

12 December 2020

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

1 reference

12 December 2020

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

1 reference

12 December 2020

Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline.

1 reference

12 December 2020

Regulation of the G2/M transition by p53.

1 reference

12 December 2020

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

12 December 2020

Participation of p53 protein in the cellular response to DNA damage

1 reference

12 December 2020

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

1 reference

12 December 2020

Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast.

1 reference

12 December 2020

rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

1 reference

12 December 2020

Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast

1 reference

12 December 2020

Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion.

1 reference

12 December 2020

Activation of multiple protein kinases during the burst in protein phosphorylation that precedes the first meiotic cell division in Xenopus oocytes

1 reference

12 December 2020

Toward maintaining the genome: DNA damage and replication checkpoints

1 reference

12 December 2020

p53: puzzle and paradigm

1 reference

12 December 2020

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

1 reference

12 December 2020

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

12 December 2020

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

1 reference

12 December 2020

1 reference

12 December 2020

Rb function in cell-cycle regulation and apoptosis

1 reference

12 December 2020

Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase

1 reference

12 December 2020

Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity

1 reference

12 December 2020

Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe

1 reference

12 December 2020

Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells

1 reference

12 December 2020

A Rad3–Rad26 complex responds to DNA damage independently of other checkpoint proteins

1 reference

12 December 2020

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

1 reference

12 December 2020

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

1 reference

12 December 2020

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

1 reference

12 December 2020

Genetic control of the cell division cycle in yeast

1 reference

12 December 2020

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

1 reference

12 December 2020

Induction of early mitotic events in a cell-free system

1 reference

12 December 2020

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

12 December 2020

Cell-Cycle Dependence of Two Nuclear Histone Kinase Enzyme Activities

1 reference

12 December 2020

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1 reference

12 December 2020

Cdc25 protein phosphatases in cell proliferation

1 reference

12 December 2020

Regulation of mitotic inhibitor Mik1 helps to enforce the DNA damage checkpoint

1 reference

12 December 2020

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

1 reference

12 December 2020

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

1 reference

12 December 2020

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

12 December 2020

Cytoplasmic factor responsible for germinal vesicle breakdown and meiotic maturation in starfish oocyte

1 reference

12 December 2020

Evidence for a second cell cycle block at G2/M by p53.

1 reference

12 December 2020

Mechanism by which caffeine potentiates lethality of nitrogen mustard

1 reference

12 December 2020

Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome

1 reference

12 December 2020

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

12 December 2020

Epistatic gene interactions in the control of division in fission yeast

1 reference

12 December 2020

Role of protein synthesis and proteases in production and inactivation of maturation-promoting activity during meiotic maturation of starfish oocytes

1 reference

12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

12 December 2020

Surfing the p53 network

1 reference

12 December 2020

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

1 reference

12 December 2020

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

1 reference

12 December 2020

G2 arrest in response to topoisomerase II inhibitors: the role of p53.

1 reference

12 December 2020

cdc25+ functions as an inducer in the mitotic control of fission yeast

1 reference

12 December 2020

Formation in vitro of sperm pronuclei and mitotic chromosomes induced by amphibian ooplasmic components

1 reference

12 December 2020

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

1 reference

12 December 2020

The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex

1 reference

12 December 2020

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

1 reference

12 December 2020

The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression

1 reference

12 December 2020

The interaction of steroids with Rana pipiens oocytes in the induction of maturation

1 reference

12 December 2020

In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression

1 reference

12 December 2020

p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells

1 reference

12 December 2020

Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

1 reference

12 December 2020

The molecular basis for cell cycle delays following ionizing radiation: a review

1 reference

12 December 2020

Identifiers

DOI

10.1385/MB:32:3:227

2 references

23 March 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1028778673

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16632889

1 reference

Consolidated OpenCitations Corpus – April 2017