(Q28237811)

12 December 2020

Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment.

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12 December 2020

Molecular cloning and expression of rat contraception associated protein 1 (CAP1), a protein putatively involved in fertilization

1 reference

12 December 2020

ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation

1 reference

12 December 2020

Mitochondrial involvement in Parkinson's disease

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12 December 2020

Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36.

1 reference

12 December 2020

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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12 December 2020

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

1 reference

12 December 2020

DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

1 reference

12 December 2020

Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study

1 reference

12 December 2020

The JNK signal transduction pathway

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12 December 2020

PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

1 reference

12 December 2020

Complete genomic screen in Parkinson disease: evidence for multiple genes.

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12 December 2020

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

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12 December 2020

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

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12 December 2020

Parallel and comparative analysis of the proteome and transcriptome of sorbic acid-stressed Saccharomyces cerevisiae.

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12 December 2020

Identification of gel-separated tumor marker proteins by mass spectrometry

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12 December 2020

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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12 December 2020

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12 December 2020

DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor

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12 December 2020

Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation

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12 December 2020

Oxidative stress, spermatogenesis and fertility

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12 December 2020

Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

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12 December 2020

Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat

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12 December 2020

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

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12 December 2020

Age at onset in two common neurodegenerative diseases is genetically controlled

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12 December 2020

Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions

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12 December 2020

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

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12 December 2020

DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice

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12 December 2020

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

1 reference

12 December 2020

SP22: a novel fertility protein from a highly conserved gene family.

1 reference

12 December 2020

A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

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12 December 2020

Crystal structure of DJ-1/RS and implication on familial Parkinson's disease

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12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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12 December 2020

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

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12 December 2020

Protein misfolding and degradation in genetic diseases.

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12 December 2020

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

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12 December 2020

Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron

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12 December 2020

The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

1 reference

12 December 2020

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

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12 December 2020

The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes

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12 December 2020

The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease

1 reference

12 December 2020

A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

alpha-Synuclein locus triplication causes Parkinson's disease

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12 December 2020

Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?

1 reference

12 December 2020

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

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12 December 2020

alpha-synuclein promotes mitochondrial deficit and oxidative stress

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12 December 2020

Identification of RS as a flagellar and head sperm protein

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12 December 2020

Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion

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12 December 2020

Identification of genes that modify ataxin-1-induced neurodegeneration.

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12 December 2020

Impairment of the ubiquitin-proteasome system by protein aggregation

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12 December 2020

Mouse and fly models of neurodegeneration

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12 December 2020

Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: an 18F-dopa PET study

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12 December 2020

Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease

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12 December 2020

GAPDH knockdown rescues mesencephalic dopaminergic neurons from MPP+ -induced apoptosis

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12 December 2020

Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease

1 reference

12 December 2020

DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia

1 reference

12 December 2020

Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene.

1 reference

12 December 2020

A susceptibility gene for late-onset idiopathic Parkinson's disease

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12 December 2020

Chaperone-mediated protein folding

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12 December 2020

Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae

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12 December 2020

Identification and characterization of a SUMO-1 conjugation system that modifies neuronal calcium/calmodulin-dependent protein kinase II in Drosophila melanogaster

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12 December 2020

Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations.

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12 December 2020

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

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12 December 2020

A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1.

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12 December 2020

Enhanced SUMOylation in polyglutamine diseases.

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12 December 2020

The 1.6-A crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad

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12 December 2020

Versatile protein tag, SUMO: its enzymology and biological function

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12 December 2020

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

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12 December 2020

Phenotypic characterisation of autosomal recessive PARK6-linked parkinsonism in three unrelated Italian families

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12 December 2020

Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter

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12 December 2020

alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells

1 reference

12 December 2020

Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome

1 reference

12 December 2020

The ubiquitin pathway in Parkinson's disease

1 reference

12 December 2020

L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system

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12 December 2020

Association between early-onset Parkinson's disease and mutations in the parkin gene

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12 December 2020

Signal transduction by the JNK group of MAP kinases

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12 December 2020

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

1 reference

12 December 2020

The role of pathogenic DJ-1 mutations in Parkinson's disease.

1 reference

12 December 2020

Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations

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12 December 2020

Nuclear localization of overexpressed glyceraldehyde-3-phosphate dehydrogenase in cultured cerebellar neurons undergoing apoptosis.

1 reference

12 December 2020

Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q.

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12 December 2020

Alpha-synuclein and neurodegenerative diseases

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12 December 2020

Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila

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12 December 2020

Low external pH induces HOG1-dependent changes in the organization of the Saccharomyces cerevisiae cell wall.

1 reference

12 December 2020

DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin

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12 December 2020

Parkin disease: a phenotypic study of a large case series

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12 December 2020

The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases

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12 December 2020

Mutations in NR4A2 associated with familial Parkinson disease

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12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Rare genetic mutations shed light on the pathogenesis of Parkinson disease

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12 December 2020

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

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12 December 2020

Possible redox regulation of sperm motility activation.

1 reference

12 December 2020

Significant linkage of Parkinson disease to chromosome 2q36-37

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12 December 2020

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

1 reference

12 December 2020

DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex

1 reference

12 December 2020

Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36

1 reference

12 December 2020

Detection of cathepsin B up-regulation in neoplastic thyroid tissues by proteomic analysis

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12 December 2020

Parkinson's disease. First of two parts

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12 December 2020

Identification and characterization of a novel protein that regulates RNA-protein interaction

1 reference

12 December 2020

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

1 reference

12 December 2020

Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates

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12 December 2020

Clinical features and neuroimaging of PARK7-linked parkinsonism

1 reference

12 December 2020

Recent advances in the genetics and pathogenesis of Parkinson disease

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12 December 2020

Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain

1 reference

12 December 2020

Prevalence of Parkinson's disease in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group

1 reference

12 December 2020

Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36

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12 December 2020

A susceptibility locus for Parkinson's disease maps to chromosome 2p13.

1 reference

12 December 2020

Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset

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12 December 2020

Psychiatric symptoms in Parkinson's disease

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12 December 2020