(Q28269219)

https://api.crossref.org/works/10.1177%2F0091270006292125

CYP3A4 induction by xenobiotics: biochemistry, experimental methods and impact on drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Pharmacokinetic interactions with rifampicin : clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Identification of the novel splicing variants for the hPXR in human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

The nuclear receptor superfamily: the second decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Functional characterization of a novel polymorphism of pregnane X receptor, Q158K, in Chinese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Extreme discordant phenotype methodology: an intuitive approach to clinical pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Nuclear receptor expression in fetal and pediatric liver: correlation with CYP3A expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Factors influencing midazolam hydroxylation activity in human liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125

Eleven Novel Single Nucleotide Polymorphisms in the NRH2 (PXR) Gene, Pour of which Induce Non-synonymous Amino Acid Alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006292125