(Q28277703)

Daniele Santini

2

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Alfonso Baldi

Alfonso Baldi

7

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Emanuele Dragonetti

5

Emanuele Dragonetti

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Raffaele Murace

4

Raffaele Murace

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Enrico Spugnini

6

Enrico P Spugnini

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author name string

Mara Campioni

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1

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language of work or name

English

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publication date

November 2005

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published in

Experimental Dermatology

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volume

14

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issue

11

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page(s)

811-8

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cites work

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Bim: a novel member of the Bcl-2 family that promotes apoptosis

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

20 April 2017

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Apaf-1 deficiency and neural tube closure defects are found in fog mice

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Definition of a consensus binding site for p53

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

A model for p53-induced apoptosis

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Genomic analysis of metastasis reveals an essential role for RhoC

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Control of apoptosis and mitotic spindle checkpoint by survivin

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

Analysis of APAF-1 expression in human cutaneous melanoma progression

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1600-0625.2005.00360.X

20 April 2017

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

IAP proteins: blocking the road to death's door

20 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Use of a cDNA microarray to analyse gene expression patterns in human cancer

20 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Molecular classification of cutaneous malignant melanoma by gene expression profiling

20 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Methylation-induced repression--belts, braces, and chromatin

20 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).

20 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Programmed cell death and apoptosis: origins of the theory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Apoptotic pathways: the roads to ruin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Caspase-9 and APAF-1 form an active holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

The regulation of APAF1 expression during development and tumourigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

The Bcl-2 protein family: arbiters of cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Apaf-1 is a mediator of E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Initiation of Apaf-1 translation by internal ribosome entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Protein factor requirements of the Apaf-1 internal ribosome entry segment: roles of polypyrimidine tract binding protein and upstream of N-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Apoptosis and melanoma chemoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

21 January 2018

Apoptosis and therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Drug-resistance in human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Ferritin contributes to melanoma progression by modulating cell growth and sensitivity to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

cDNA array technology in melanoma: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

The pathogenesis of melanoma induced by ultraviolet radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Non-lesional vitiliginous melanocytes are not characterized by an increased proneness to nitric oxide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Apoptosis and melanoma: molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Apoptosis regulators and responses in human melanocytic and keratinocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

The p16INK4a/CDKN2A tumor suppressor and its relatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Human melanocyte senescence and melanoma susceptibility genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Mutations in the TP53 gene in human malignant melanomas derived from sun-exposed skin and unexposed mucosal membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Role of caspases-3 and -7 in Apaf-1 proteolytic cleavage and degradation events during cisplatin-induced apoptosis in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Allelic imbalance of 12q22-23 associated with APAF-1 locus correlates with poor disease outcome in cutaneous melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Regulators of apoptosis: suitable targets for immune therapy of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2005.00360.X