(Q28307066)

Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations

31 March 2020

1 reference

Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity

31 March 2020

1 reference

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

31 March 2020

1 reference

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

31 March 2020

2 references

31 March 2020

12 December 2020

The bounty of RAGs: recombination signal complexes and reaction outcomes

1 reference

Identification of basic residues in RAG2 critical for DNA binding by the RAG1-RAG2 complex

31 March 2020

1 reference

Assembly of the RAG1/RAG2 synaptic complex

31 March 2020

1 reference

Ordered assembly of the V(D)J synaptic complex ensures accurate recombination

31 March 2020

1 reference

V(D)J recombination: RAG proteins, repair factors, and regulation

31 March 2020

1 reference

Accessibility control of V(D)J recombination

31 March 2020

1 reference

Factors and forces controlling V(D)J recombination

31 March 2020

1 reference

Regulation of the assembly and expression of variable-region genes

31 March 2020

1 reference

Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus

31 March 2020

1 reference

Monoallelic gene expression: a repertoire of recurrent themes

31 March 2020

1 reference

T cell development: better living through chromatin

31 March 2020

1 reference

Regulating antigen-receptor gene assembly

31 March 2020

1 reference

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

31 March 2020

1 reference

Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1.

31 March 2020

1 reference

Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase

31 March 2020

1 reference

Stimulation of V(D)J recombination by histone acetylation

31 March 2020

1 reference

Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA

31 March 2020

1 reference

ATP-dependent remodeling by SWI/SNF and ISWI proteins stimulates V(D)J cleavage of 5 S arrays

31 March 2020

1 reference

Acetylation increases access of remodelling complexes to their nucleosome targets to enhance initiation of V(D)J recombination.

31 March 2020

1 reference

Activation of 12/23-RSS-dependent RAG cleavage by hSWI/SNF complex in the absence of transcription

31 March 2020

1 reference

Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences

31 March 2020

1 reference

Transcription-dependent mobilization of nucleosomes at accessible TCR gene segments in vivo

31 March 2020

1 reference

The DNA-encoded nucleosome organization of a eukaryotic genome

31 March 2020

1 reference

What controls nucleosome positions?

31 March 2020

1 reference

Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo

31 March 2020

1 reference

Poly(dA:dT) tracts: major determinants of nucleosome organization

31 March 2020

1 reference

Regulation of immunoglobulin heavy-chain gene rearrangements

31 March 2020

1 reference

Mechanics of T cell receptor gene rearrangement

31 March 2020

1 reference

Chromatin architecture and the generation of antigen receptor diversity

31 March 2020

1 reference

Regulation of activation and recombination of the murine Igkappa locus

31 March 2020

1 reference

Regulation of T cell receptor-alpha gene recombination by transcription

31 March 2020

1 reference

Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination

31 March 2020

1 reference

Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility

31 March 2020

1 reference

The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate

31 March 2020

1 reference

Antisense intergenic transcription in V(D)J recombination

31 March 2020

1 reference

Antisense intergenic transcription precedes Igh D-to-J recombination and is controlled by the intronic enhancer Emu.

31 March 2020

1 reference

Repeat organization and epigenetic regulation of the DH-Cmu domain of the immunoglobulin heavy-chain gene locus

31 March 2020

1 reference

Cutting edge: SWI/SNF mediates antisense Igh transcription and locus-wide accessibility in B cell precursors

31 March 2020

1 reference

Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination

31 March 2020

1 reference

How to keep V(D)J recombination under control

31 March 2020

1 reference

A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation

31 March 2020

1 reference

Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4

31 March 2020

1 reference

B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5

31 March 2020

1 reference

The establishment and maintenance of lymphocyte identity through gene silencing

31 March 2020

1 reference

Nucleosome displacement in transcription

31 March 2020

1 reference

The role of chromatin during transcription

31 March 2020

1 reference

High-resolution profiling of histone methylations in the human genome

31 March 2020

1 reference

Histone H4-K16 acetylation controls chromatin structure and protein interactions

31 March 2020

1 reference

DNA translocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC.

31 March 2020

1 reference

Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition.

31 March 2020

1 reference

Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes

31 March 2020

1 reference

Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments

31 March 2020

1 reference

Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility

31 March 2020

1 reference

Form follows function: The genomic organization of cellular differentiation

31 March 2020

1 reference

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

31 March 2020

1 reference

Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development

31 March 2020

1 reference

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes

31 March 2020

1 reference

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

31 March 2020

1 reference

Epigenetic ontogeny of the Igk locus during B cell development

31 March 2020

1 reference

Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments

31 March 2020

1 reference

Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells

31 March 2020

1 reference

Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene

31 March 2020

1 reference

Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion

31 March 2020

1 reference

Biallelic germline transcription at the kappa immunoglobulin locus

31 March 2020

1 reference

Biallelic, ubiquitous transcription from the distal germline Ig{kappa} locus promoter during B cell development

31 March 2020

1 reference

Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.

31 March 2020

1 reference

Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

31 March 2020

1 reference

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

31 March 2020

1 reference

The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions.

31 March 2020

1 reference

Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination

31 March 2020

1 reference

The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis

31 March 2020

1 reference

A PHD finger motif in the C terminus of RAG2 modulates recombination activity

31 March 2020

1 reference

A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination

31 March 2020

1 reference

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

31 March 2020

1 reference

A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement

31 March 2020

1 reference

Mutations in conserved regions of the predicted RAG2 kelch repeats block initiation of V(D)J recombination and result in primary immunodeficiencies

31 March 2020

1 reference

H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations

31 March 2020

1 reference

Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination

31 March 2020

1 reference

The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci.

31 March 2020

1 reference

A non-sequence-specific DNA binding mode of RAG1 is inhibited by RAG2

31 March 2020

1 reference

Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination

31 March 2020

1 reference

The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining

31 March 2020

1 reference

A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex

31 March 2020

1 reference

RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination

31 March 2020

1 reference

RAG: a recombinase diversified

31 March 2020

1 reference

Rag mutations reveal robust alternative end joining

31 March 2020

2 references

31 March 2020

12 December 2020

Linking double-stranded DNA breaks to the recombination activating gene complex directs repair to the nonhomologous end-joining pathway

1 reference

Evidence for Ku70/Ku80 association with full-length RAG1.

31 March 2020

1 reference

Single-strand recombination signal sequence nicks in vivo: evidence for a capture model of synapsis

31 March 2020

1 reference

Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis

31 March 2020

1 reference

Mechanistic basis for coding end sequence effects in the initiation of V(D)J recombination

31 March 2020

1 reference

Initiation of V(D)J recombination by Dbeta-associated recombination signal sequences: a critical control point in TCRbeta gene assembly

31 March 2020

1 reference

RSSsite: a reference database and prediction tool for the identification of cryptic Recombination Signal Sequences in human and murine genomes

31 March 2020

1 reference

Non-B DNA structure-induced genetic instability and evolution

31 March 2020

1 reference

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

31 March 2020

1 reference

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells

31 March 2020

1 reference

rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent

31 March 2020

1 reference

Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

31 March 2020

1 reference

Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair

31 March 2020

1 reference

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

31 March 2020

1 reference

Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1

31 March 2020

1 reference

Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination

31 March 2020

1 reference

Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development

31 March 2020

1 reference

Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

31 March 2020

1 reference

Regulation of TCRbeta gene assembly by a promoter/enhancer holocomplex

31 March 2020

1 reference

Promoter activation by enhancer-dependent and -independent loading of activator and coactivator complexes

31 March 2020

1 reference

Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter

31 March 2020

1 reference

Deletion of germline promoter PD beta 1 from the TCR beta locus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms.

31 March 2020

1 reference

Differential activation of dual promoters alters Dbeta2 germline transcription during thymocyte development

31 March 2020

1 reference

Promoter activity 5' of Dbeta2 is coordinated by E47, Runx1, and GATA-3.

31 March 2020

1 reference

Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes

31 March 2020

1 reference

Targeted inhibition of V(D)J recombination by a histone methyltransferase

31 March 2020

1 reference

PubMed

12 December 2020

A developmental stage-specific promoter directs germline transcription of D beta J beta gene segments in precursor T lymphocytes

1 reference

PubMed

12 December 2020