(Q28386736)

5 July 2017

title

Phase diagrams describing fibrillization by polyalanine peptides (English)

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5 July 2017

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Hung D Nguyen

1

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5 July 2017

Carol K Hall

series ordinal

2

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5 July 2017

language of work or name

English

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publication date

1 October 2004

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5 July 2017

number of pages

13

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inferred from page(s)

published in

Biophysical Journal

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5 July 2017

volume

87

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5 July 2017

issue

6

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5 July 2017

page(s)

4122-4134

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The structural basis of protein folding and its links with human disease

5 July 2017

cites work

1 reference

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20 March 2017

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Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides

20 March 2017

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Assembly and kinetic folding pathways of a tetrameric beta-sheet complex: molecular dynamics simulations on simplified off-lattice protein models

29 September 2017

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Mechanism for the alpha-helix to beta-hairpin transition

29 September 2017

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Why is Leu55-->Pro55 transthyretin variant the most amyloidogenic: insights from molecular dynamics simulations of transthyretin monomers

29 September 2017

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The role of side-chain interactions in the early steps of aggregation: Molecular dynamics simulations of an amyloid-forming peptide from the yeast prion Sup35

29 September 2017

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Simulations of human lysozyme: probing the conformations triggering amyloidosis

29 September 2017

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Short peptide amyloid organization: stabilities and conformations of the islet amyloid peptide NFGAIL

29 September 2017

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Molecular dynamics simulation of the SH3 domain aggregation suggests a generic amyloidogenesis mechanism

29 September 2017

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Stabilities and conformations of Alzheimer's beta -amyloid peptide oligomers (Abeta 16-22, Abeta 16-35, and Abeta 10-35): Sequence effects

29 September 2017

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Molecular dynamics simulations of alanine rich beta-sheet oligomers: Insight into amyloid formation

29 September 2017

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Amyloid-fibril formation. Proposed mechanisms and relevance to conformational disease

29 September 2017

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Charge states rather than propensity for beta-structure determine enhanced fibrillogenesis in wild-type Alzheimer's beta-amyloid peptide compared to E22Q Dutch mutant

29 September 2017

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Long time dynamic simulations: exploring the folding pathways of an Alzheimer's amyloid Abeta-peptide

29 September 2017

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Exploring protein aggregation and self-propagation using lattice models: phase diagram and kinetics

29 September 2017

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Probing the origins of increased activity of the E22Q "Dutch" mutant Alzheimer's beta-amyloid peptide

29 September 2017

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alpha-helix formation: discontinuous molecular dynamics on an intermediate-resolution protein model

29 September 2017

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Simulation study of the structure and dynamics of the Alzheimer's amyloid peptide congener in solution

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Three-helix-bundle protein in a Ramachandran model

29 September 2017

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Oculopharyngeal muscular dystrophy

29 September 2017

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Amyloid fibrillogenesis: themes and variations

29 September 2017

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Temperature dependence of amyloid beta-protein fibrillization

29 September 2017

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Protein aggregation: folding aggregates, inclusion bodies and amyloid

29 September 2017

1 reference

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Mutations and off-pathway aggregation of proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation

29 September 2017

1 reference

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Thermal stabilities of globular proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Solvent effects on the conformational transition of a model polyalanine peptide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Molecular simulation of the primary and secondary structures of the Abeta(1-42)-peptide of Alzheimer's disease.

2 June 2018

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The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

2 June 2018

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The structure of amyloid fibrils by electron microscopy and X-ray diffraction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Polyalanine-based peptides as models for self-associated beta-pleated-sheet complexes

2 June 2018

1 reference

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Deadly conformations--protein misfolding in prion disease

2 June 2018

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Thermodynamics and stability of a beta-sheet complex: molecular dynamics simulations on simplified off-lattice protein models

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

The sequence dependence of fiber organization. A comparative molecular dynamics study of the islet amyloid polypeptide segments 22-27 and 22-29.

27 November 2018

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Structural and dynamical analysis of the hydration of the Alzheimer's beta-amyloid peptide.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Towards an understanding of amyloidogenesis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Protein refolding versus aggregation: computer simulations on an intermediate-resolution protein model

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Assembly of a tetrameric alpha-helical bundle: computer simulations on an intermediate-resolution protein model

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Thermodynamics of model prions and its implications for the problem of prion protein folding

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Formation of an extremely stable polyalanine beta-sheet macromolecule

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304921

Activation barriers to structural transition determine deposition rates of Alzheimer's disease a beta amyloid

27 November 2018

1 reference

12 December 2020

Solvent environment conducive to protein aggregation

1 reference

12 December 2020

Dynamics and fluidity of amyloid fibrils: a model of fibrous protein aggregates

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12 December 2020

Computationally derived structural models of the beta-amyloid found in Alzheimer's disease plaques and the interaction with possible aggregation inhibitors

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12 December 2020

Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro

1 reference

12 December 2020

Kinetics and thermodynamics of folding of a de novo designed four-helix bundle protein

1 reference

12 December 2020

Conformational studies of human islet amyloid peptide using molecular dynamics and simulated annealing methods

1 reference

12 December 2020

10.1529/BIOPHYSJ.104.047159

Identifiers

DOI

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5 July 2017

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5 July 2017

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