(Q28393157)

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Pre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brain

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Pre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brain (English)

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Tobias K Karakach

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367541%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

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Barry E Kennedy

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367541%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Veronique G LeBlanc

2

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Europe PubMed Central

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12 June 2020

Tiffany M Mailman

3

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Europe PubMed Central

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12 June 2020

Debra Fice

4

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12 June 2020

Ian Burton

5

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12 June 2020

Barbara Karten

7

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12 June 2020

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2013

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12 June 2020

8

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12 June 2020

12

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12 June 2020

e82685

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Europe PubMed Central

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12 June 2020

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Creative Commons Attribution 4.0 International

18 December 2013

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Early alterations of brain cellular energy homeostasis in Huntington disease models

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Oxidative stress: a pathogenic mechanism for Niemann-Pick type C disease

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The pyruvate dehydrogenase complex as a therapeutic target for age-related diseases

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Early glial activation, synaptic changes and axonal pathology in the thalamocortical system of Niemann-Pick type C1 mice

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Brain lactate metabolism: the discoveries and the controversies

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Neurodegeneration as a consequence of failed mitochondrial maintenance

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Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications.

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Pyruvate dehydrogenase deficiency and epilepsy

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In vivo evidence for lactate as a neuronal energy source

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Anatomically defined neuron-based rescue of neurodegenerative Niemann-Pick type C disorder.

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Niemann-Pick Type C2 protein contributes to the transport of endosomal cholesterol to mitochondria without interacting with NPC1.

1 reference

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2 June 2018

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1 reference

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2 June 2018

Unesterified cholesterol accumulation in late endosomes/lysosomes causes neurodegeneration and is prevented by driving cholesterol export from this compartment

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2 June 2018

High brain lactate is not caused by a shift in the lactate dehydrogenase A/B ratio

1 reference

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2 June 2018

DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination

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2 June 2018

Generation and function of astroglial lipoproteins from Niemann-Pick type C1-deficient mice

1 reference

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2 June 2018

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

1 reference

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2 June 2018

Fatty acid oxidation in rat brain is limited by the low activity of 3-ketoacyl-coenzyme A thiolase

1 reference

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2 June 2018

Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Altered cholesterol metabolism in Niemann-Pick type C1 mouse brains affects mitochondrial function

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Close coupling between astrocytic and neuronal metabolisms to fulfill anaplerotic and energy needs in the rat brain

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Molecular characterization of zebrafish embryogenesis via DNA microarrays and multiplatform time course metabolomics studies.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Postnatal development of inflammation in a murine model of Niemann-Pick type C disease: immunohistochemical observations of microglia and astroglia

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Metabonomic characterization of the 3-nitropropionic acid rat model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Adult onset Niemann-Pick type C disease: A clinical, neuroimaging and molecular genetic study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Over-expression of heme oxygenase-1 promotes oxidative mitochondrial damage in rat astroglia

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

An analysis of variance test for normality (complete samples)

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0082685

21 January 2018

Allosteric regulation of PKM2 allows cellular adaptation to different physiological states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

(1)H NMR based metabolomics of CSF and blood serum: a metabolic profile for a transgenic rat model of Huntington disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

Neuroimaging findings in a brain with Niemann-Pick type C disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

Pre-synaptic defects of NPC1-deficient hippocampal neurons are not directly related to plasma membrane cholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

Evaluation of lactate as a marker of metabolic stress and cause of secondary damage in acute ischemic stroke or TIA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3867386

27 November 2018

Neurodegeneration in the Niemann-Pick C mouse: glial involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/24367541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in urinary metabolites due to unilateral ureteral obstruction in a rodent model

1 reference

https://pubmed.ncbi.nlm.nih.gov/24367541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/24367541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suitability of 2-deoxyglucose for measuring initial rates of glucose uptake in isolated adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24367541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathologic changes of glial cells in murine model of Niemann-Pick disease type C: immunohistochemical, lectin-histochemical and ultrastructural observations

1 reference

https://pubmed.ncbi.nlm.nih.gov/24367541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/24367541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick disease type C: unique 2-deoxy-2[¹⁸F] fluoro-D-glucose PET abnormality

1 reference

https://pubmed.ncbi.nlm.nih.gov/24367541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat brain and liver mitochondria develop oxidative stress and lose enzymatic activities on aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/24367541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0082685

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367541%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

2013PLoSO...882685K

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367541%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367541%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

ResearchGate publication ID

0 references

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