(Q28477194)

1

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Keli Agama

2

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Laurence P G Wakelin

3

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Renate Griffith

Creative Commons CC0 License

5

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language of work or name

English

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publication date

2011

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published in

PLOS One

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volume

6

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issue

9

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page(s)

e25150

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copyright license

start time

22 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

1 reference

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Cellular roles of dna topoisomerases: a molecular perspective

19 March 2017

1 reference

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178613

Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

19 March 2017

1 reference

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A model for the mechanism of human topoisomerase I

19 March 2017

1 reference

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Development and validation of a genetic algorithm for flexible docking

19 March 2017

1 reference

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DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

19 March 2017

1 reference

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The NCI60 human tumour cell line anticancer drug screen

7 April 2017

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Topoisomerase I inhibitors: camptothecins and beyond

7 April 2017

1 reference

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Design, Synthesis, and Evaluation of Dibenzo[c,h][1,6]naphthyridines as Topoisomerase I Inhibitors and Potential Anticancer Agents

7 April 2017

1 reference

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Pharmacophore based drug design approach as a practical process in drug discovery

24 May 2017

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Pharmacophore modeling and applications in drug discovery: challenges and recent advances

29 September 2017

1 reference

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Structure-based design, synthesis, and biological studies of new anticancer norindenoisoquinoline topoisomerase I inhibitors

29 September 2017

1 reference

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Structure-based drug design strategies in medicinal chemistry

29 September 2017

1 reference

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The indenoisoquinoline noncamptothecin topoisomerase I inhibitors: update and perspectives

29 September 2017

1 reference

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The binding orientation of a norindenoisoquinoline in the topoisomerase I-DNA cleavage complex is primarily governed by pi-pi stacking interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178613

Molecule-pharmacophore superpositioning and pattern matching in computational drug design

29 September 2017

1 reference

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Novel stable camptothecin derivatives replacing the E-ring lactone by a ketone function are potent inhibitors of topoisomerase I and promising antitumor drugs

29 September 2017

1 reference

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Oncology exploration: charting cancer medicinal chemistry space

29 September 2017

1 reference

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A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex

29 September 2017

1 reference

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Synthesis and mechanism of action studies of a series of norindenoisoquinoline topoisomerase I poisons reveal an inhibitor with a flipped orientation in the ternary DNA-enzyme-inhibitor complex as determined by X-ray crystallographic analysis

29 September 2017

1 reference

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Non-camptothecin DNA topoisomerase I inhibitors in cancer therapy

29 September 2017

1 reference

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Homocamptothecins: potent topoisomerase I inhibitors and promising anticancer drugs

29 September 2017

1 reference

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Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

29 September 2017

1 reference

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Water soluble inhibitors of topoisomerase I: quaternary salt derivatives of camptothecin

29 September 2017

1 reference

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Synthesis, topoisomerase I inhibitory activity, and in vivo evaluation of 11-azacamptothecin analogs

29 September 2017

1 reference

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Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880).

29 September 2017

1 reference

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Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor Agents

29 September 2017

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Comparative analysis of topoisomerase IB inhibition and DNA intercalation by flavonoids and similar compounds: structural determinates of activity

2 June 2018

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Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs

2 June 2018

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Renal clearance of camptothecin (NSC-100880): effect of urine volume

2 June 2018

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Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

2 June 2018

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Mechanisms of camptothecin resistance by human topoisomerase I mutations

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025150

Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex

21 January 2018

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DNA cleavage assay for the identification of topoisomerase I inhibitors

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025150

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025150

Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025150

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025150

Current trends in lead discovery: are we looking for the appropriate properties?

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0025150

Apoptosis induction and cell cycle perturbation in human hepatoma hep G2 cells by 10-hydroxycamptothecin

21 January 2018

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12 December 2020

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

12 December 2020

Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I

1 reference

12 December 2020

Rigid analogs of camptothecin as DNA topoisomerase I inhibitors

1 reference

12 December 2020

Studies on Nepalese Crude Drugs. XIV. New Flavonoids from the Root of Scutellaria prostrata Jacq. ex Benth.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.39.1466

Identifiers

DOI

10.1371/JOURNAL.PONE.0025150

1 reference

ADS bibcode

2011PLoSO...625150D

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1 reference

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PubMed publication ID

21966440

1 reference