(Q28478016)

Anjan Debnath

8

0 references

Adam R Renslo

Adam R Renslo

13

0 references

Philip J Rosenthal

10

Philip J Rosenthal

0 references

James H McKerrow

11

James H McKerrow

0 references

author name string

Kenny K H Ang

1

0 references

Joseline Ratnam

2

0 references

Jiri Gut

3

0 references

Jennifer Legac

4

0 references

Elizabeth Hansell

5

0 references

Katarzyna M Skrzypczynska

7

0 references

Juan C Engel

9

0 references

Michelle R Arkin

PLoS Neglected Tropical Diseases

12

0 references

language of work or name

English

0 references

publication date

3 May 2011

0 references

published in

0 references

volume

5

0 references

page(s)

e1023

0 references

issue

5

0 references

copyright license

Creative Commons Attribution 4.0 International

start time

3 May 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Evidence of Artemisinin-Resistant Malaria in Western Cambodia

19 March 2017

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Beyond picomolar affinities: quantitative aspects of noncovalent and covalent binding of drugs to proteins

19 March 2017

1 reference

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A cysteine protease inhibitor cures Chagas' disease in an immunodeficient-mouse model of infection

19 March 2017

1 reference

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Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis)

19 March 2017

1 reference

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Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3

19 March 2017

1 reference

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

19 March 2017

1 reference

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Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

19 March 2017

1 reference

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Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease

19 March 2017

1 reference

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Comparison of the antiplasmodial and falcipain-2 inhibitory activity of beta-amino alcohol thiolactone-chalcone and isatin-chalcone hybrids

29 September 2017

1 reference

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Structure-guided development of selective TbcatB inhibitors

29 September 2017

1 reference

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Covalent modifiers: an orthogonal approach to drug design

29 September 2017

1 reference

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RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model

29 September 2017

1 reference

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A parasite cysteine protease is key to host protein degradation and iron acquisition

29 September 2017

1 reference

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The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

29 September 2017

1 reference

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Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

29 September 2017

1 reference

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Target assessment for antiparasitic drug discovery

29 September 2017

1 reference

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Drug discovery and development for neglected parasitic diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Medicines for Malaria Venture: sustaining antimalarial drug development

29 September 2017

1 reference

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Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems

29 September 2017

1 reference

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Cysteine proteases of malaria parasites

29 September 2017

1 reference

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Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi

29 September 2017

1 reference

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Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum

29 September 2017

1 reference

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Antimalarial drug discovery: old and new approaches

29 September 2017

1 reference

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Nonleadlikeness and leadlikeness in biochemical screening

29 September 2017

1 reference

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Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Cysteine proteases of parasitic organisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Cysteine protease inhibitors as chemotherapy for parasitic infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.

29 September 2017

1 reference

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A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum

29 September 2017

1 reference

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Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate-economical microplate and time-dependent inhibition assays for trypanothione reductase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Risk factors for encephalopathy and mortality during melarsoprol treatment of Trypanosoma brucei gambiense sleeping sickness

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

The crystal structure of cruzain: a therapeutic target for Chagas' disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Gene disruptions demonstrate independent roles for the four falcipain cysteine proteases of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Falcipain inhibitors: optimization studies of the 2-pyrimidinecarbonitrile lead series

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Vinyl sulfones as mechanism-based cysteine protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Peptidic 1-cyanopyrrolidines: synthesis and SAR of a series of potent, selective cathepsin inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Substrate mapping and inhibitor profiling of falcipain-2, falcipain-3 and berghepain-2: implications for peptidase anti-malarial drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001023

Cysteine protease inhibitors alter Golgi complex ultrastructure and function in Trypanosoma cruzi.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Production of crystallizable cruzain, the major cysteine protease from Trypanosoma cruzi

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086806

Keto-1,3,4-oxadiazoles as cathepsin K inhibitors

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21572521

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Peptidyl fluoromethyl ketones as inhibitors of cathepsin B. Implication for treatment of rheumatoid arthritis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21572521

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chemotherapy of malaria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21572521

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PNTD.0001023

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4285719

OpenCitations bibliographic resource ID

4285719

1 reference