(Q28487027)

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Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs

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scholarly article

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Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs (English)

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object named as

Sun Choi

2

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José L. Medina-Franco

3

object named as

José L Medina-Franco

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author name string

Jakyung Yoo

1

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language of work or name

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publication date

2013

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8

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e62152

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4

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copyright license

Creative Commons Attribution 4.0 International

25 April 2013

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April 2022 Public Data File from Crossref

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Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

19 March 2017

DNA methyltransferases and methyl-binding proteins of mammals

1 reference

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19 March 2017

CXXC domain of human DNMT1 is essential for enzymatic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

19 March 2017

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

19 March 2017

Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

19 March 2017

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

19 March 2017

HhaI methyltransferase flips its target base out of the DNA helix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

19 March 2017

Molecular modeling and virtual screening of DNA methyltransferase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

DNA methylation inhibitors in cancer: recent and future approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Towards the chemoinformatic-based identification of DNA methyltransferase inhibitors: 2D- and 3D-similarity profile of screening libraries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Inhibitors of DNA methyltransferases: insights from computational studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Epigenetic cancer therapy: rationales, targets and drugs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Rapid synthesis of new DNMT inhibitors derivatives of procainamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Epigenetic drug discovery: targeting DNA methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Structure and function of mammalian DNA methyltransferases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Mammalian DNA methyltransferases: a structural perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura

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29 September 2017

Procainamide is a specific inhibitor of DNA methyltransferase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

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29 September 2017

Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

DNA methylation, methyltransferases, and cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

29 September 2017

Synthesis and biochemical evaluation of δ(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636198

2 June 2018

Trapped in action: direct visualization of DNA methyltransferase activity in living cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0062152

21 January 2018

Trimethylaurintricarboxylic acid inhibits human DNA methyltransferase 1: insights from enzymatic and molecular modeling studies.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0062152

21 January 2018

Discovery of two novel, small-molecule inhibitors of DNA methylation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0062152

21 January 2018

Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0062152

21 January 2018

Molecular biology. Preference by exclusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23637988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homology modeling, docking and structure-based pharmacophore of inhibitors of DNA methyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23637988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0062152

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2013PLoSO...862152Y

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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