(Q28510523)

GOA release 2020-03-11

Presenilin 1

1 reference

GOA release 2020-03-11

author name string

Jae Yoon Leem

1

1 reference

25 January 2017

Shrijay Vijayan

2

1 reference

25 January 2017

Ping Han

3

1 reference

25 January 2017

Dongming Cai

4

1 reference

25 January 2017

Michael Machura

5

1 reference

25 January 2017

Kryslaine O. Lopes

6

1 reference

25 January 2017

Margaret L. Veselits

7

1 reference

25 January 2017

Huaxi Xu

8

1 reference

25 January 2017

Gopal Thinakaran

Journal of Biological Chemistry

9

1 reference

25 January 2017

language of work or name

English

0 references

publication date

24 May 2002

1 reference

25 January 2017

1 reference

25 January 2017

277

1 reference

25 January 2017

19236–19240

1 reference

25 January 2017

21

1 reference

25 January 2017

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Molecular genetics of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Effects of PS1 deficiency on membrane protein trafficking in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Notch receptor cleavage depends on but is not directly executed by presenilins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Metabolism of presenilins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Drosophila nicastrin is essential for the intramembranous cleavage of notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Stable association of presenilin derivatives and absence of presenilin interactions with APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Identification and synthesis of a recognition signal for the attachment of glycosaminoglycans to proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

21 January 2018

Adaptor-related proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200

Subcellular localization of presenilins: association with a unique membrane pool in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200148200