(Q28547501)

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Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy

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Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy (English)

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object named as

Carola Otth

8

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author name string

Viviana A Cavieres

1

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Alexis González

2

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Vanessa C Muñoz

3

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Claudia P Yefi

4

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Hianara A Bustamante

5

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Rafael R Barraza

6

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Cheril Tapia-Rojas

7

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María José Barrera

9

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Carlos González

10

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Gonzalo A Mardones

11

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Nibaldo C Inestrosa

12

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Patricia V Burgos

13

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language of work or name

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publication date

2015

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10

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8

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e0136313

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Creative Commons Attribution 4.0 International

26 August 2015

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April 2022 Public Data File from Crossref

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Structural and Functional Characterization of Cargo-Binding Sites on the μ4-Subunit of Adaptor Protein Complex 4

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Tyrosinase degradation is prevented when EDEM1 lacks the intrinsically disordered region

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19 March 2017

SVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagy

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19 March 2017

Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex

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A dual role for EDEM1 in the processing of rod opsin

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19 March 2017

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

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19 March 2017

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

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19 March 2017

EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin

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19 March 2017

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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19 March 2017

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

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19 March 2017

The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting.

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7 April 2017

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7 April 2017

Mitochondria supply membranes for autophagosome biogenesis during starvation

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7 April 2017

mTOR regulation of autophagy

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7 April 2017

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7 April 2017

Potential therapeutic applications of autophagy

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7 April 2017

Quality control: ER-associated degradation: protein quality control and beyond

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29 September 2017

Cycloheximide inhibits starvation-induced autophagy through mTORC1 activation

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29 September 2017

Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy

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29 September 2017

Turnover of C99 is controlled by a crosstalk between ERAD and ubiquitin-independent lysosomal degradation in human neuroglioma cells

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29 September 2017

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29 September 2017

Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease

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29 September 2017

Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.

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29 September 2017

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

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29 September 2017

Protein misfolding disorders and macroautophagy

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29 September 2017

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29 September 2017

Novel research horizons for presenilins and γ-secretases in cell biology and disease

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29 September 2017

Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation

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29 September 2017

The hyperforin derivative IDN5706 occludes spatial memory impairments and neuropathological changes in a double transgenic Alzheimer's mouse model

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29 September 2017

The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

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29 September 2017

Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection

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29 September 2017

Basal autophagy is involved in the degradation of the ERAD component EDEM1.

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29 September 2017

The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I.

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29 September 2017

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

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29 September 2017

Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities

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29 September 2017

HDAC6 at the intersection of autophagy, the ubiquitin-proteasome system and neurodegeneration

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29 September 2017

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

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29 September 2017

Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

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29 September 2017

Hyperforin prevents beta-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-beta-deposits

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29 September 2017

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29 September 2017

Coated vesicles transport newly synthesized membrane glycoproteins from endoplasmic reticulum to plasma membrane in two successive stages

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29 September 2017

Starvation and inhibition of lysosomal function increased tau secretion by primary cortical neurons

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3 June 2018

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3 June 2018

Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing.

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3 June 2018

Hypericum extract and hyperforin: memory-enhancing properties in rodents

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21 January 2018

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers.

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21 January 2018

Herpes simplex virus type 1 induces simultaneous activation of Toll-like receptors 2 and 4 and expression of the endogenous ligand serum amyloid A in astrocytes.

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Utilizing flow cytometry to monitor autophagy in living mammalian cells

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Generation of tau aggregates and clearance by autophagy in an inducible cell model of tauopathy

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Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response

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Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that int

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https://pubmed.ncbi.nlm.nih.gov/26308941

12 December 2020

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inferred from PubMed ID database lookup

Effects of brefeldin A on autophagy in cultured rat fibroblasts

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https://pubmed.ncbi.nlm.nih.gov/26308941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0136313

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2015PLoSO..1036313C

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release_v46yqgfsyfagxffvhm2qti6vde

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https://api.fatcat.wiki/v0/release/v46yqgfsyfagxffvhm2qti6vde

24 November 2022

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

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