(Q28576068)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

A bridging interaction allows calmodulin to activate NO synthase through a bi-modal mechanism (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

author name string

Mohammad Mahfuzul Haque

series ordinal

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Deborah Durra

series ordinal

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Dennis J Stuehr

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

language of work or name

English

0 references

publication date

7 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

number of pages

9

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

volume

285

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

issue

34

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

page(s)

25941-25949

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

Protein interactions in the human methionine synthase-methionine synthase reductase complex and implications for the mechanism of enzyme reactivation

4 February 2020

cites work

1 reference

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SWISS-MODEL: An automated protein homology-modeling server

17 March 2017

1 reference

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Extensive conformational sampling in a ternary electron transfer complex

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Nitric oxide synthases: structure, function and inhibition

17 March 2017

1 reference

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Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Structure of nitric oxide synthase oxygenase dimer with pterin and substrate

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transfer

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Regulation of interdomain interactions by calmodulin in inducible nitric-oxide synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Regulation of interdomain electron transfer in the NOS output state for NO production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Neutralizing a surface charge on the FMN subdomain increases the activity of neuronal nitric-oxide synthase by enhancing the oxygen reactivity of the enzyme heme-nitric oxide complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Regulation of FMN subdomain interactions and function in neuronal nitric oxide synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Intraprotein electron transfer in inducible nitric oxide synthase holoenzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Differences in a conformational equilibrium distinguish catalysis by the endothelial and neuronal nitric-oxide synthase flavoproteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Dynamics driving function: new insights from electron transferring flavoproteins and partner complexes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Direct measurement by laser flash photolysis of intraprotein electron transfer in a rat neuronal nitric oxide synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Nitric-oxide synthase: a cytochrome P450 family foster child

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Intraprotein electron transfer in a two-domain construct of neuronal nitric oxide synthase: the output state in nitric oxide formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Direct measurement by laser flash photolysis of intramolecular electron transfer in a two-domain construct of murine inducible nitric oxide synthase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Update on mechanism and catalytic regulation in the NO synthases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Nitric-oxide synthase (NOS) reductase domain models suggest a new control element in endothelial NOS that attenuates calmodulin-dependent activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Mapping the interactions between flavodoxin and its physiological partners flavodoxin reductase and cobalamin-dependent methionine synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Mammalian nitric oxide synthases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Characterization of the reductase domain of rat neuronal nitric oxide synthase generated in the methylotrophic yeast Pichia pastoris. Calmodulin response is complete within the reductase domain itself

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Differential binding of calmodulin domains to constitutive and inducible nitric oxide synthase enzymes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923985

Importance of the domain-domain interface to the catalytic action of the NO synthase reductase domain

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Calmodulin activates electron transfer through neuronal nitric-oxide synthase reductase domain by releasing an NADPH-dependent conformational lock

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Versatile regulation of neuronal nitric oxide synthase by specific regions of its C-terminal tail.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

The function of the small insertion in the hinge subdomain in the control of constitutive mammalian nitric-oxide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

The FAD-shielding residue Phe1395 regulates neuronal nitric-oxide synthase catalysis by controlling NADP+ affinity and a conformational equilibrium within the flavoprotein domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Neuronal nitric-oxide synthase mutant (Ser-1412 --> Asp) demonstrates surprising connections between heme reduction, NO complex formation, and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Neuronal nitric-oxide synthase interaction with calmodulin-troponin C chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Differential activation of nitric-oxide synthase isozymes by calmodulin-troponin C chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Binding and activation of nitric oxide synthase isozymes by calmodulin EF hand pairs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Structural Elements Contribute to the Calcium/Calmodulin Dependence on Enzyme Activation in Human Endothelial Nitric-oxide Synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Differences in three kinetic parameters underpin the unique catalytic profiles of nitric-oxide synthases I, II, and III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

A kinetic simulation model that describes catalysis and regulation in nitric-oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Electron transfer by neuronal nitric-oxide synthase is regulated by concerted interaction of calmodulin and two intrinsic regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

The C termini of constitutive nitric-oxide synthases control electron flow through the flavin and heme domains and affect modulation by calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

The C terminus of mouse macrophage inducible nitric-oxide synthase attenuates electron flow through the flavin domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.126797

Role of reductase domain cluster 1 acidic residues in neuronal nitric-oxide synthase. Characterization of the FMN-FREE enzyme

21 January 2018

1 reference

12 December 2020

Surface charge interactions of the FMN module govern catalysis by nitric-oxide synthase

1 reference

12 December 2020

Conformational and Thermodynamic Control of Electron Transfer in Neuronal Nitric Oxide Synthase†

1 reference

12 December 2020

Space, time and nitric oxide--neuronal nitric oxide synthase generates signal pulses

1 reference

12 December 2020

Nitric Oxide: Chemical Puzzles Posed by a Biological Messenger

1 reference

12 December 2020

Calmodulin controls neuronal nitric-oxide synthase by a dual mechanism. Activation of intra- and interdomain electron transfer

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.126797

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20529840%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

2 references

31 January 2017