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Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
title
Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression
(English)
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
main subject
Presenilin 2
1 reference
stated in
GOA release 2020-03-11
Amyloid beta (A4) precursor protein
1 reference
stated in
GOA release 2020-03-11
Presenilin 1
1 reference
stated in
GOA release 2020-03-11
Amyloid beta (A4) precursor-like protein 2
1 reference
stated in
GOA release 2020-03-11
author name string
Yun-wu Zhang
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
Ruishan Wang
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
Qiang Liu
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
Han Zhang
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
Francesca-Fang Liao
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
Huaxi Xu
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
language of work or name
English
0 references
publication date
19 June 2007
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
volume
104
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stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
page(s)
10613–10618
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stated in
PubMed
PubMed ID
17556541
retrieved
31 January 2017
issue
25
1 reference
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PubMed
PubMed ID
17556541
retrieved
31 January 2017
cites work
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PubMed Central
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AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis
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PubMed Central
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Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP
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Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components
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PubMed Central
reference URL
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PubMed Central
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17 March 2017
APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development
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PubMed Central
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Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
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17 March 2017
Nicastrin Is Required for Assembly of Presenilin/γ-Secretase Complexes to Mediate Notch Signaling and for Processing and Trafficking of β-Amyloid Precursor Protein in Mammals
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PubMed Central
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17 March 2017
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein
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PubMed Central
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The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner
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PubMed Central
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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
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17 March 2017
Mice lacking both presenilin genes exhibit early embryonic patterning defects
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17 March 2017
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
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PubMed Central
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17 March 2017
Skeletal and CNS defects in Presenilin-1-deficient mice
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17 March 2017
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
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17 March 2017
EGF-ERBB signalling: towards the systems level
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Targeting epidermal growth factor receptor signaling in the treatment of head and neck cancer
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29 September 2017
Pathological and physiological functions of presenilins
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PubMed Central
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Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes
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PubMed Central
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29 September 2017
Notch1 is essential for postimplantation development in mice.
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C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.
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21 January 2018
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
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Crossref
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21 January 2018
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.
1 reference
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Crossref
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21 January 2018
Metabolism of the "Swedish" amyloid precursor protein variant in Madin-Darby canine kidney cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17556541
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17556541
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0703903104
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3896001
ADS bibcode
2007PNAS..10410613Z
0 references
OpenCitations bibliographic resource ID
3896001
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3896001
PMCID
1888796
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3896001
PubMed ID
17556541
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3896001
ResearchGate publication ID
6279446
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