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FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
title
FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development
(English)
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
main subject
TGFB-induced factor homeobox 1
1 reference
stated in
GOA release 2020-03-11
Kruppel-like factor 5
1 reference
stated in
GOA release 2020-03-11
F-box and WD-40 domain protein 7
1 reference
stated in
GOA release 2020-03-11
Lamin B1
1 reference
stated in
GOA release 2020-03-11
author
Gordon Stamp
series ordinal
5
0 references
Bradley Spencer-Dene
series ordinal
3
0 references
Annabelle Lewis
object named as
Annabelle Lewis
series ordinal
2
0 references
Axel Behrens
object named as
Axel Behrens
series ordinal
6
0 references
Ian Tomlinson
series ordinal
7
object named as
Ian Tomlinson
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
author name string
Hayley Davis
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
Hilda Tateossian
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
publication date
1 June 2011
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
published in
Journal of Pathology
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
volume
224
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
issue
2
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stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
page(s)
180–189
1 reference
stated in
PubMed
PubMed ID
21503901
retrieved
31 January 2017
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3757315/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
WD40 Repeat Propellers Define a Ubiquitin-Binding Domain that Regulates Turnover of F Box Proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
C/EBPalpha is required for lung maturation at birth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
Genomic sequencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
17 March 2017
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
7 April 2017
Tumor suppressor Fbxw7 regulates TGFβ signaling by targeting TGIF1 for degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Transforming growth-interacting factor (TGIF) regulates proliferation and differentiation of human myeloid leukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Krüppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Kruppel-like factor 5 is required for perinatal lung morphogenesis and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
The Fbxw7/hCdc4 tumor suppressor in human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Fbw7/hCDC4 dimerization regulates its substrate interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Mechanisms of tumor suppression by the SCF(Fbw7).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Foxa2 is required for transition to air breathing at birth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Cleft palate: players, pathways, and pursuits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Myc degradation: dancing with ubiquitin ligases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Inactivation of hCDC4 can cause chromosomal instability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Lung development in the mouse embryo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
29 September 2017
Developmental expression of the mouse gene coding for the Krüppel-like transcription factor KLF5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757315
retrieved
3 June 2018
Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
FBXW7/hCDC4 is a general tumor suppressor in human cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FPATH.2874
retrieved
21 January 2018
The prenatal development of the mouse eye
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21503901
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/PATH.2874
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4865690
OpenCitations bibliographic resource ID
4865690
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4865690
PMCID
3757315
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4865690
PubMed ID
21503901
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4865690
ResearchGate publication ID
51061594
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