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Rac1 controls the subcellular localization of the Rho guanine nucleotide exchange factor Net1A to regulate focal adhesion formation and cell spreading
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scholarly article
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PubMed
PubMed ID
23184663
retrieved
31 January 2017
title
Rac1 controls the subcellular localization of the Rho guanine nucleotide exchange factor Net1A to regulate focal adhesion formation and cell spreading
(English)
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PubMed
PubMed ID
23184663
retrieved
31 January 2017
main subject
Rac family small GTPase 1
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stated in
GOA release 2020-03-11
guanine
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author name string
Heather S. Carr
series ordinal
1
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stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
Christopher A. Morris
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
Sarita Menon
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
Eun Hyeon Song
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
Jeffrey A. Frost
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
language of work or name
English
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publication date
1 February 2013
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PubMed
PubMed ID
23184663
retrieved
31 January 2017
published in
Molecular and Cellular Biology
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PubMed
PubMed ID
23184663
retrieved
31 January 2017
volume
33
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stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
page(s)
622–634
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stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
issue
3
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stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
describes a project that uses
ImageJ
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Europe PubMed Central
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11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3554212/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
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PTP-PEST couples membrane protrusion and tail retraction via VAV2 and p190RhoGAP.
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Rho GTPases: biochemistry and biology
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PubMed Central
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PAK1 negatively regulates the activity of the Rho exchange factor NET1
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Rho and Rac take center stage
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The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation
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Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
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Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA
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Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins
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Rho GTPases and their effector proteins
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Activation of Rac and Cdc42 by integrins mediates cell spreading
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7 April 2017
Coordination of Rho GTPase activities during cell protrusion
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7 April 2017
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7 April 2017
Direct effect of morphine on breast cancer cell function in vitro: role of the NET1 gene
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29 September 2017
Life at the leading edge
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29 September 2017
Smad3 regulates Rho signaling via NET1 in the transforming growth factor-beta-induced epithelial-mesenchymal transition of human retinal pigment epithelial cells
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Interaction of the RhoA exchange factor Net1 with discs large homolog 1 protects it from proteasome-mediated degradation and potentiates Net1 activity
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29 September 2017
Coexpression of alpha6beta4 integrin and guanine nucleotide exchange factor Net1 identifies node-positive breast cancer patients at high risk for distant metastasis
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29 September 2017
NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer
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29 September 2017
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29 September 2017
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29 September 2017
Receptor activation alters inner surface potential during phagocytosis
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29 September 2017
RAS and RHO GTPases in G1-phase cell-cycle regulation
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PubMed Central
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29 September 2017
Rho proteins and cancer
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PubMed Central
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29 September 2017
Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma.
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PubMed Central
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29 September 2017
Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters
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PubMed Central
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29 September 2017
Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554212
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29 September 2017
Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation
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PubMed Central
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29 September 2017
A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin.
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3 June 2018
Analysis of activated GAPs and GEFs in cell lysates
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3 June 2018
The Rho exchange factor Net1 is regulated by nuclear sequestration
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3 June 2018
Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1.
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3 June 2018
Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition.
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27 November 2018
Over-expression of neuroepithelial-transforming protein 1 confers poor prognosis of patients with gliomas.
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27 November 2018
Expression and clinical significance of NET-1 and PCNA in hepatocellular carcinoma.
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27 November 2018
Overexpression of βPix-a in human breast cancer tissues
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27 November 2018
The integrin beta tail is required and sufficient to regulate adhesion signaling to Rac1.
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27 November 2018
Rho GTPases are over-expressed in human tumors.
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PubMed Central
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27 November 2018
Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23184663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Examination of human tumors for rhoA mutations
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23184663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.00980-12
1 reference
stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
PMCID
3554212
0 references
PubMed ID
23184663
1 reference
stated in
PubMed
PubMed ID
23184663
retrieved
31 January 2017
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