(Q28608346)

1

0 references

Kevin N Lu

2

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Shi-Yuan Cheng

3

0 references

Bo Hu

4

0 references

Xiaojun Ma

5

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Nicholas Nystrom

6

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Xinghua Lu

PLOS Computational Biology

7

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language of work or name

English

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publication date

August 2015

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published in

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volume

11

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issue

8

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page(s)

e1004257

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copyright license

Creative Commons Attribution 4.0 International

start time

28 August 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening

17 March 2017

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Integrated genomic analyses of ovarian carcinoma

17 March 2017

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Identifying causal genes and dysregulated pathways in complex diseases

17 March 2017

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Hallmarks of Cancer: The Next Generation

17 March 2017

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DEGAS: de novo discovery of dysregulated pathways in human diseases

17 March 2017

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Somatic mutations affect key pathways in lung adenocarcinoma

17 March 2017

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

17 March 2017

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Molecular basis of the VHL hereditary cancer syndrome

17 March 2017

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The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway

17 March 2017

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Gene ontology: tool for the unification of biology

17 March 2017

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17 March 2017

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

17 March 2017

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MYC on the path to cancer

7 April 2017

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Reverse engineering of regulatory networks in human B cells

7 April 2017

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An exact algorithm for finding cancer driver somatic genome alterations: the weighted mutually exclusive maximum set cover problem

9 May 2017

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Conceptualization of molecular findings by mining gene annotations

29 September 2017

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The regulation of MDM2 oncogene and its impact on human cancers

29 September 2017

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Identifying potential cancer driver genes by genomic data integration

29 September 2017

1 reference

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RETRACTED: Investigation of the hub genes and related mechanism in ovarian cancer via bioinformatics analysis

29 September 2017

1 reference

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Pan-cancer patterns of somatic copy number alteration

29 September 2017

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Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor

29 September 2017

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Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells.

29 September 2017

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Simultaneous identification of multiple driver pathways in cancer

29 September 2017

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From data towards knowledge: revealing the architecture of signaling systems by unifying knowledge mining and data mining of systematic perturbation data

29 September 2017

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Module cover - a new approach to genotype-phenotype studies.

29 September 2017

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MDM2, MDMX and p53 in oncogenesis and cancer therapy

29 September 2017

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Elevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcome

29 September 2017

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29 September 2017

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Low-density lipoprotein receptor-related protein-1 (LRP1) mediates autophagy and apoptosis caused by Helicobacter pylori VacA

29 September 2017

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MuSiC: identifying mutational significance in cancer genomes

29 September 2017

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Discovery of mutated subnetworks associated with clinical data in cancer.

29 September 2017

1 reference

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Mutual exclusivity analysis identifies oncogenic network modules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

De novo discovery of mutated driver pathways in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

29 September 2017

1 reference

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Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors

29 September 2017

1 reference

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Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Identifying informative subsets of the Gene Ontology with information bottleneck methods

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Neurofibroma development in NF1--insights into tumour initiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

PIK3CA mutations and copy number gains in human lung cancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Overexpression of the centrosomal protein Aurora-A kinase is associated with poor prognosis in epithelial ovarian cancer patients.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Modelling the molecular circuitry of cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Intranuclear compartmentalization of cyclin E during the cell cycle: disruption of the nucleoplasm-nucleolar shuttling of cyclin E in bladder cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

MDM2 oncogene as a target for cancer therapy: An antisense approach

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Intracranial gliomas in neurofibromatosis type 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Shared gene expression alterations in prostate cancer and histologically benign prostate from patients with prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552843

Algorithms for detecting significantly mutated pathways in cancer.

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1004257

Efficient methods for identifying mutated driver pathways in cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1004257

MLLT3 regulates early human erythroid and megakaryocytic cell fate

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1004257

10.1371/JOURNAL.PCBI.1004257

21 January 2018

Identifiers

DOI

1 reference

journals/ploscb/LuLCHMNL15

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

1 reference

PubMed publication ID

26317392

1 reference