(Q28743461)

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Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma

scientific article (publication date: 18 January 2011)

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20 January 2020

Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma (English)

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20 January 2020

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20 January 2020

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20 January 2020

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Eric C Holland

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20 January 2020

Michelle Bradbury

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Michelle S Bradbury

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20 January 2020

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Craig J Galbán

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20 January 2020

Stefanie Galbán

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20 January 2020

Fei Li

5

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20 January 2020

Nikki Charles

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20 January 2020

Oren J Becher

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20 January 2020

Thomas L Chenevert

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20 January 2020

Alnawaz Rehemtulla

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20 January 2020

Brian D Ross

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20 January 2020

Dolores Hambardzumyan

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20 January 2020

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18 January 2011

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20 January 2020

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20 January 2020

6

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20 January 2020

1

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20 January 2020

e14545

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20 January 2020

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Creative Commons Attribution 4.0 International

18 January 2011

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Europe PubMed Central

11 June 2022

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based on heuristic

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

1 reference

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Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma

1 reference

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16 March 2017

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

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7 April 2017

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Phase I/II trial of pyrazoloacridine and carboplatin in patients with recurrent glioma: a North Central Cancer Treatment Group trial.

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Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo

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3 June 2018

mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21267448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II trial of perifosine in locally advanced, unresectable, or metastatic pancreatic adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21267448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0014545

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20 January 2020

2011PLoSO...614545P

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Europe PubMed Central

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20 January 2020

PubMed publication ID

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Europe PubMed Central

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20 January 2020

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