(Q30080035)

English

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

scientific article published on 24 July 2010

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scholarly article

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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial (English)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20609467

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Rita Schmutzler

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object named as

Schmutzler RK

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Jeffrey N Weitzel

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object named as

Weitzel JN

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28 May 2017

2

object named as

Robson M

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author name string

Tutt A

1

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Garber JE

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Domchek SM

4

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Audeh MW

5

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Friedlander M

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Arun B

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Loman N

9

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Wardley A

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Mitchell G

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Earl H

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Wickens M

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Carmichael J

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language of work or name

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28 May 2017

publication date

24 July 2010

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28 May 2017

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376

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235-44

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28 May 2017

9737

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20609467

28 May 2017

Epidemiology of breast cancer. Findings from the nurses' health study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Breast cancer and hormone-replacement therapy in the Million Women Study

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Genome-wide association study identifies novel breast cancer susceptibility loci

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

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Identification of the breast cancer susceptibility gene BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical management of BRCA1 and BRCA2 mutation carriers

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Brca1 controls homology-directed DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

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Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA2 is required for homology-directed repair of chromosomal breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of Brca2 increases the spontaneous mutation rate in vivo: synergism with ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic genetic alterations inBRCA2-associated and sporadic male breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCAl-linked families. The Breast Cancer Linkage Consortium

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The concept of synthetic lethality in the context of anticancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The pathology of familial breast cancer: Immunohistochemistry and molecular analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Sensitivity to first-line chemotherapy for metastatic breast cancer in BRCA1 and BRCA2 mutation carriers

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Multicentre, phase II study evaluating capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Vinorelbine (navelbine) as a salvage treatment for advanced breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to therapy caused by intragenic deletion in BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960892-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0140-6736(10)60892-6

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20609467

28 May 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20609467

28 May 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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