(Q30157152)

English

Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: thermodynamic and mechanistic catalysts of kinase activation by cancer mutations

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scholarly article

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Europe PubMed Central

PMC publication ID

13 November 2017

Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: thermodynamic and mechanistic catalysts of kinase activation by cancer mutations (English)

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Europe PubMed Central

PMC publication ID

13 November 2017

Gennady Verkhivker

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Gennady M Verkhivker

2

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author name string

Anshuman Dixit

1

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Europe PubMed Central

PMC publication ID

13 November 2017

publication date

28 August 2009

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Europe PubMed Central

PMC publication ID

13 November 2017

PLOS Computational Biology

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Europe PubMed Central

PMC publication ID

13 November 2017

5

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

8

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

e1000487

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Europe PubMed Central

PMC publication ID

13 November 2017

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Creative Commons Attribution 4.0 International

28 August 2009

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April 2022 Public Data File from Crossref

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

1 reference

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High-throughput oncogene mutation profiling in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Conformational substates modulate hydride transfer in dihydrofolate reductase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Computational detection of the binding-site hot spot at the remodeled human growth hormone-receptor interface.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Monte Carlo simulations of the peptide recognition at the consensus binding site of the constant fragment of human immunoglobulin G: the energy landscape analysis of a hot spot at the intermolecular interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722018

26 November 2018

Protein Conformational Transitions: The Closure Mechanism of a Kinase Explored by Atomistic Simulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19714203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detailed conformational dynamics of juxtamembrane region and activation loop in c-Kit kinase activation process

1 reference

https://pubmed.ncbi.nlm.nih.gov/19714203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PCBI.1000487

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

DBLP publication ID

journals/ploscb/DixitV09

1 reference

DBLP Dataset 2021-01-02

28 January 2021

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

ResearchGate publication ID

0 references

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