(Q30248743)

13 June 2017

3 references

13 July 2022

22 October 2022

MERS-CoV spike protein: Targets for vaccines and therapeutics (English)

1 reference

Middle East respiratory syndrome coronavirus

13 June 2017

0 references

0 references

1

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11 June 2020

4

Jinghua Yan

1 reference

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11 June 2020

3

Guangwen Lu

1 reference

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11 June 2020

author name string

Gary Wong

series ordinal

2

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11 June 2020

George F Gao

series ordinal

5

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11 June 2020

language of work or name

1 reference

25 July 2016

1 reference

PubMed ID

27468951

13 June 2017

1 September 2016

2 references

13 July 2022

22 October 2022

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27468951%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

13 July 2022

22 October 2022

133

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11 June 2020

page(s)

165-177

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Coronavirus avian infectious bronchitis virus

11 June 2020

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The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists

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Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virus-neutralizing antibodies

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Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.

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Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26

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Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

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Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein

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Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

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SARS: systematic review of treatment effects

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Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

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The spike protein of SARS-CoV--a target for vaccine and therapeutic development

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Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques

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12 December 2020

Animal models of Middle East respiratory syndrome coronavirus infection

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Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease

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Evaluation of candidate vaccine approaches for MERS-CoV.

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12 December 2020

A review of palivizumab and emerging therapies for respiratory syncytial virus

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Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1

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12 December 2020

Potent neutralization of Hendra and Nipah viruses by human monoclonal antibodies

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12 December 2020

Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development

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12 December 2020

Alphavirus-based vaccines

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12 December 2020

Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease

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12 December 2020

Effect of amino acid replacements, additions and deletions on the antiviral activity of a peptide derived from the HIV-1 GP41 sequence

1 reference

12 December 2020

Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)-Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

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3-Hydroxyphthalic anhydride-modified human serum albumin as a microbicide candidate inhibits HIV infection by blocking viral entry

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Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus.

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A trimeric subdomain of the simian immunodeficiency virus envelope glycoprotein

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Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

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Chemically modified bovine beta-lactoglobulin inhibits human papillomavirus infection

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Therapeutic proteins.

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Mechanisms of coronavirus cell entry mediated by the viral spike protein

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Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

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Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution

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Pre-fusion structure of a human coronavirus spike protein.

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Peptide vaccines against cancer, infectious diseases, and conception

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High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

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Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

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12 December 2020

Coronavirus immunogens

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Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme

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12 December 2020

Middle East respiratory syndrome: obstacles and prospects for vaccine development

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12 December 2020

Fusion core structure of the severe acute respiratory syndrome coronavirus (SARS-CoV): in search of potent SARS-CoV entry inhibitors

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An animal model of MERS produced by infection of rhesus macaques with MERS coronavirus

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DNA vaccines in veterinary use.

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Conditionals by inversion provide a universal method for the generation of conditional alleles

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12 December 2020

Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus

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12 December 2020

A review of feline infectious peritonitis virus: molecular biology, immunopathogenesis, clinical aspects, and vaccination

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Functional importance of the coiled-coil of the Ebola virus glycoprotein

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12 December 2020

Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein

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Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection

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The "common cold" in frail older persons: impact of rhinovirus and coronavirus in a senior daycare center

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12 December 2020

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The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies

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12 December 2020

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12 December 2020

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12 December 2020

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

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12 December 2020

Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin

1 reference

12 December 2020

Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments--the importance of immunofocusing in subunit vaccine design

1 reference

12 December 2020

HIV-1 inhibition by a peptide

1 reference

12 December 2020

Bat-to-human: spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyond

1 reference

12 December 2020

Structure of SARS coronavirus spike receptor-binding domain complexed with receptor

1 reference

12 December 2020

A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates

1 reference

12 December 2020

Design of Potential RNAi (miRNA and siRNA) Molecules for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Gene Silencing by Computational Method

1 reference

12 December 2020

Inhibition of feline immunodeficiency virus infection in vitro by envelope glycoprotein synthetic peptides

1 reference

12 December 2020

Identification of a new human coronavirus

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12 December 2020

Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia

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12 December 2020

An overview of successful TGEV vaccination strategies and discussion on the interrelationship between TGEV and PRCV

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12 December 2020

Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

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12 December 2020

Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus

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12 December 2020

Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors

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12 December 2020

The many mechanisms of viral membrane fusion proteins.

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12 December 2020

An outbreak of coronavirus OC43 respiratory infection in Normandy, France

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12 December 2020

A new virus isolated from the human respiratory tract

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12 December 2020

Antibacterial monoclonal antibodies: the next generation?

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12 December 2020

A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates

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12 December 2020

MERS in South Korea and China: a potential outbreak threat?

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12 December 2020

Evidence for camel-to-human transmission of MERS coronavirus

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12 December 2020

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12 December 2020

Development of chemical inhibitors of the SARS coronavirus: viral helicase as a potential target

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12 December 2020

Respiratory coronavirus infections in children younger than two years of age.

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12 December 2020

Developments in Viral Vector-Based Vaccines

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12 December 2020

Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease

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12 December 2020

Drug design targeting the main protease, the Achilles' heel of coronaviruses

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12 December 2020

Recent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery

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12 December 2020

Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

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12 December 2020

Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27

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12 December 2020

An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels

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A Computational Approach for Predicting Role of Human MicroRNAs in MERS-CoV Genome.

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12 December 2020

Canine viral vaccines at a turning point--a personal perspective

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12 December 2020

Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013.

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12 December 2020

Clinical development of Modified Vaccinia virus Ankara vaccines

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12 December 2020

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12 December 2020

ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation

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10.1016/J.ANTIVIRAL.2016.07.015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27468951%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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11 June 2020

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