(Q30418699)

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Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis (English)

1 reference

Europe PubMed Central

11 August 2017

object named as

Naoko Tanese

8

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ORCID Public Data File 2021

author name string

Brady P Culver

1

1 reference

Europe PubMed Central

11 August 2017

Jeffrey N Savas

2

1 reference

Europe PubMed Central

11 August 2017

Sung K Park

3

1 reference

Europe PubMed Central

11 August 2017

Jeong H Choi

4

1 reference

Europe PubMed Central

11 August 2017

Shuqiu Zheng

5

1 reference

Europe PubMed Central

11 August 2017

Scott O Zeitlin

6

1 reference

Europe PubMed Central

11 August 2017

John R Yates

7

1 reference

Europe PubMed Central

11 August 2017

language of work or name

0 references

publication date

3 May 2012

1 reference

Europe PubMed Central

11 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

11 August 2017

287

1 reference

Europe PubMed Central

11 August 2017

26

1 reference

Europe PubMed Central

11 August 2017

21599-21614

1 reference

Europe PubMed Central

11 August 2017

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1 reference

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Extremely long-lived nuclear pore proteins in the rat brain

1 reference

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Neurodegenerative processes in Huntington's disease

1 reference

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A yeast functional screen predicts new candidate ALS disease genes

1 reference

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Modifiers of mutant huntingtin aggregation: functional conservation of C. elegans-modifiers of polyglutamine aggregation

1 reference

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Huntington's disease: can mice lead the way to treatment?

1 reference

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Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization.

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Huntington's disease: a clinical review

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Driving biochemical discovery with quantitative proteomics.

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1 reference

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A role for huntington disease protein in dendritic RNA granules

1 reference

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Role of spectral counting in quantitative proteomics.

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Huntingtin as an essential integrator of intracellular vesicular trafficking

1 reference

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Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

1 reference

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Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies.

1 reference

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Significance analysis of spectral count data in label-free shotgun proteomics

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Huntington's disease: from pathology and genetics to potential therapies

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A quantitative analysis software tool for mass spectrometry-based proteomics

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Synaptosome proteomics

1 reference

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Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

1 reference

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Quantification of the synaptosomal proteome of the rat cerebellum during post-natal development

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Huntingtin interacting proteins are genetic modifiers of neurodegeneration

1 reference

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BDNF-mediated neurotransmission relies upon a myosin VI motor complex

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Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway

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Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes

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A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

1 reference

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1 reference

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

1 reference

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PANTHER: a library of protein families and subfamilies indexed by function

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Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

1 reference

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Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS

1 reference

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1 reference

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1 reference

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Large-scale analysis of the yeast proteome by multidimensional protein identification technology

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The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381125

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Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381125

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1 reference

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Huntingtin interacts with a family of WW domain proteins

1 reference

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1 reference

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Characterization and localization of the Huntington disease gene product

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1 reference

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Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

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Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

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Myosin-Va facilitates the accumulation of mRNA/protein complex in dendritic spines.

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Functional gene expression profiling in yeast implicates translational dysfunction in mutant huntingtin toxicity.

1 reference

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Mitochondrial defect in Huntington's disease caudate nucleus

1 reference

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Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue

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Identifiers

10.1074/JBC.M112.359307

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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