(Q30435534)

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N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats

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Europe PubMed Central

PMC publication ID

15 October 2017

N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Colleen M. Niswender

9

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Colleen M Niswender

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Europe PubMed Central

PMC publication ID

15 October 2017

P. Jeffrey Conn

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P Jeffrey Conn

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Europe PubMed Central

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15 October 2017

Craig W. Lindsley

11

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Craig W Lindsley

1 reference

Europe PubMed Central

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15 October 2017

5

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Hyekyung P Cho

1 reference

Europe PubMed Central

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15 October 2017

Alice L. Rodriguez

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Alice L Rodriguez

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Daryl F Venable

4

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Daryl F Venable

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Europe PubMed Central

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15 October 2017

Ryan R. Morrison

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Ryan D Morrison

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Europe PubMed Central

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15 October 2017

Kyle A. Emmitte

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Kyle A Emmitte

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Europe PubMed Central

PMC publication ID

15 October 2017

Kimberly M Lovell

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Kimberly M Lovell

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Europe PubMed Central

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15 October 2017

author name string

Andrew S Felts

2

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Europe PubMed Central

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15 October 2017

Frank W Byers

7

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15 October 2017

J Scott Daniels

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15 October 2017

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17 May 2013

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Europe PubMed Central

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15 October 2017

Bioorganic & Medicinal Chemistry Letters

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Europe PubMed Central

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15 October 2017

23

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Europe PubMed Central

PMC publication ID

15 October 2017

13

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

3713-3718

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells

1 reference

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Recent advances in the medicinal chemistry of the metabotropic glutamate receptor 1 (mGlu₁)

1 reference

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Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous system function.

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Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

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1 reference

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Synthesis and SAR of a mGluR5 allosteric partial antagonist lead: unexpected modulation of pharmacology with slight structural modifications to a 5-(phenylethynyl)pyrimidine scaffold

1 reference

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Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma

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Correlation between brain/plasma ratios and efficacy in neuropathic pain models of selective metabotropic glutamate receptor 1 antagonists

1 reference

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20 June 2018

Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators.

1 reference

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20 June 2018

Pharmacological characterization of stress-induced hyperthermia in DBA/2 mice using metabotropic and ionotropic glutamate receptor ligands

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20 June 2018

Radioligand binding properties and pharmacological characterization of 6-amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective, and noncompetitive antagonist of metabotropic glutamate recep

1 reference

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20 June 2018

The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles

1 reference

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20 June 2018

Positive and negative allosteric modulation of metabotropic glutamate receptors: emerging therapeutic potential

1 reference

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20 June 2018

Pharmacological agents acting at subtypes of metabotropic glutamate receptors

1 reference

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Pharmacology and functions of metabotropic glutamate receptors

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1 reference

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12 December 2020

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10.1016/J.BMCL.2013.05.020

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

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