(Q30465008)

English

NAAG peptidase inhibitors block cognitive deficit induced by MK-801 and motor activation induced by d-amphetamine in animal models of schizophrenia.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22850437%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

NAAG peptidase inhibitors block cognitive deficit induced by MK-801 and motor activation induced by d-amphetamine in animal models of schizophrenia (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22850437%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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cognitive deficit

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based on heuristic

inferred from title

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9 February 2020

Caterina P Profaci

11

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9 February 2020

author name string

R T Olszewski

1

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9 February 2020

K J Janczura

2

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9 February 2020

S R Ball

3

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9 February 2020

J C Madore

4

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9 February 2020

K M Lavin

5

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9 February 2020

J C-M Lee

6

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9 February 2020

M J Lee

7

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9 February 2020

T J Hark

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9 February 2020

P R Farago

10

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9 February 2020

T Bzdega

12

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9 February 2020

J H Neale

13

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9 February 2020

publication date

31 July 2012

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9 February 2020

Translational Psychiatry

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9 February 2020

2

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9 February 2020

e145

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22850437%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Spontaneous object recognition and its relevance to schizophrenia: a review of findings from pharmacological, genetic, lesion and developmental rodent models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

N-acetylaspartylglutamate is an agonist at mGluR₃ in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Advances in understanding the peptide neurotransmitter NAAG and appearance of a new member of the NAAG neuropeptide family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Declarative memory deficits and schizophrenia: problems and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Group II mGluR agonist LY354740 and NAAG peptidase inhibitor effects on prepulse inhibition in PCP and D-amphetamine models of schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

The role of serotonin in the NMDA receptor antagonist models of psychosis and cognitive impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Disruption of performance in the five-choice serial reaction time task induced by administration of N-methyl-D-aspartate receptor antagonists: relevance to cognitive dysfunction in schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Mouse behavioral endophenotypes for schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Metabotropic glutamate2/3 (mGlu2/3) receptors, schizophrenia and cognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Metabotropic glutamate receptors: physiology, pharmacology, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Learning and generalization in schizophrenia: effects of disease and antipsychotic drug treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Differential expression of metabotropic glutamate receptors 2 and 3 in schizophrenia: a mechanism for antipsychotic drug action?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Localization of NAAG-related gene expression deficits to the anterior hippocampus in schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Progress in the discovery and development of glutamate carboxypeptidase II inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Glutamate and schizophrenia: phencyclidine, N-methyl-D-aspartate receptors, and dopamine-glutamate interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Pharmacological and pharmacokinetic properties of a structurally novel, potent, and selective metabotropic glutamate 2/3 receptor agonist: in vitro characterization of agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxyli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Lifetime prevalence of psychotic and bipolar I disorders in a general population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

The neurobiology of cognition in schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

A dopaminergic deficit hypothesis of schizophrenia: the path to discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

NAAG peptidase inhibitors and their potential for diagnosis and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

The neurotransmitter N-acetylaspartylglutamate in models of pain, ALS, diabetic neuropathy, CNS injury and schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

28 July 2018

Animal models: inside the minds of mice and men.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Interaction of mGlu2/3 agonism with clozapine and lurasidone to restore novel object recognition in subchronic phencyclidine-treated rats.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Effects of olanzapine, sertindole and clozapine on MK-801 induced visual memory deficits in mice.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Asenapine improves phencyclidine-induced object recognition deficits in the rat: evidence for engagement of a dopamine D1 receptor mechanism

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

mGluR3 and not mGluR2 receptors mediate the efficacy of NAAG peptidase inhibitor in validated model of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Phencyclidine and dizocilpine induced behaviors reduced by N-acetylaspartylglutamate peptidase inhibition via metabotropic glutamate receptors

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039).

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

The mGluR2/3 agonist LY379268 reverses post-weaning social isolation-induced recognition memory deficits in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

The difference in effect of mGlu2/3 and mGlu5 receptor agonists on cognitive impairment induced by MK-801.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

A multicenter, inpatient, phase 2, double-blind, placebo-controlled dose-ranging study of LY2140023 monohydrate in patients with DSM-IV schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

The role of 5-hydroxytryptamine 7 receptors in the phencyclidine-induced novel object recognition deficit in rats

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Progress and prospects: stem cells and neurological diseases

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Design of NAALADase inhibitors: a novel neuroprotective strategy

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Differential effects of the N-methyl-d-aspartate receptor antagonist MK-801 on different stages of object recognition memory in mice.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

NAAG peptidase inhibitor reduces acute neuronal degeneration and astrocyte damage following lateral fluid percussion TBI in rats

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Distinct contributions of glutamate and dopamine receptors to temporal aspects of rodent working memory using a clinically relevant task

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Blockade of the metabotropic glutamate 2/3 receptors enhances social memory via the AMPA receptor in rats.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Use of MGLUR2 and MGLUR3 knockout mice to explore in vivo receptor specificity of the MGLUR2/3 selective antagonist LY341495.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.68

21 January 2018

Blockade of dopamine D₃ but not D₂ receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

26 November 2018

Association between genetic variants of the metabotropic glutamate receptor 3 (GRM3) and cognitive set shifting in healthy individuals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410622

26 November 2018

Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22850437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing

1 reference

https://pubmed.ncbi.nlm.nih.gov/22850437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22850437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiology of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22850437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22850437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/TP.2012.68

1 reference

https://api.fatcat.wiki/v0/release/ngneceyjp5di7bdmbajlqjy4j4

30 July 2022

based on heuristic

mapped directly with Wikidata item

Dimensions Publication ID

0 references

release_ngneceyjp5di7bdmbajlqjy4j4

1 reference

https://api.fatcat.wiki/v0/release/ngneceyjp5di7bdmbajlqjy4j4

30 July 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

https://api.fatcat.wiki/v0/release/ngneceyjp5di7bdmbajlqjy4j4

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/ngneceyjp5di7bdmbajlqjy4j4

30 July 2022

based on heuristic

mapped directly with Wikidata item

ResearchGate publication ID

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