(Q30494064)

English

Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy (English)

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

viral persistence

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anti-retroviral agent

0 references

Simian immunodeficiency virus

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1 reference

based on heuristic

inferred from title

Maria Letizia Barreca

4

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Barbara Chirullo

object named as

Barbara Chirullo

6

0 references

1

object named as

Mark G Lewis

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Andrea Savarino

11

object named as

Andrea Savarino

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

author name string

Sandro Norelli

2

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Matt Collins

3

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Nunzio Iraci

5

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Jake Yalley-Ogunro

7

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Jack Greenhouse

8

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Fausto Titti

9

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Enrico Garaci

10

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

publication date

16 March 2010

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

21

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

describes a project that uses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=PMC2853490

Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Dynamics of viral replication in blood and lymphoid tissues during SIVmac251 infection of macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

RT-SHIV, an infectious CCR5-tropic chimeric virus suitable for evaluating HIV reverse transcriptase inhibitors in macaque models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

A simian immunodeficiency virus-infected macaque model to study viral reservoirs that persist during highly active antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Induced-fit docking approach provides insight into the binding mode and mechanism of action of HIV-1 integrase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Characterization and structural analysis of HIV-1 integrase conservation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Novel humanized murine models for HIV research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Functional and structural characterization of the integrase from the prototype foamy virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Response of feline immunodeficiency virus (FIV) to tipranavir may provide new clues for development of broad-based inhibitors of retroviral proteases acting on drug-resistant HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Raltegravir with optimized background therapy for resistant HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Modeling, analysis, and validation of a novel HIV integrase structure provide insights into the binding modes of potent integrase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Phylogeny.fr: robust phylogenetic analysis for the non-specialist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Patented HIV-1 integrase inhibitors (1998-2005).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication in vitro and provide a rationale to redesign antiretroviral treatment for feline AIDS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Impact of antiretroviral treatment on gene expression in peripheral blood mononuclear cells from SIVmac251-infected macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

A historical sketch of the discovery and development of HIV-1 integrase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

TreeDyn: towards dynamic graphics and annotations for analyses of trees

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

HAART-persistent HIV-1 latent reservoirs: their origin, mechanisms of stability and potential strategies for eradication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Novel procedure for modeling ligand/receptor induced fit effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

MUSCLE: a multiple sequence alignment method with reduced time and space complexity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Can HIV be Cured? Mechanisms of HIV persistence and strategies to combat it.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Mosaic genomes of the six major primate lentivirus lineages revealed by phylogenetic analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Anti-HIV effects of chloroquine: mechanisms of inhibition and spectrum of activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Genetically divergent strains of human immunodeficiency virus type 2 use multiple coreceptors for viral entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

Tetrazolium-based plaque assay for HIV-1 and HIV-2, and its use in the evaluation of antiviral compounds.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

20 June 2018

HIV-1 IN alternative molecular recognition of DNA induced by raltegravir resistance mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

[Pharmacokinetics and interactions of raltegravir].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Isentress equal to Sustiva in first line therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Analysis of binding parameters of HIV-1 integrase inhibitors: correlates of drug inhibition and resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Evolution of raltegravir resistance during therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Quasispecies variant dynamics during emergence of resistance to raltegravir in HIV-1-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Characterization of vaginal transmission of a simian human immunodeficiency virus (SHIV) encoding the reverse transcriptase gene from HIV-1 in Chinese rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Selection of the Q148R integrase inhibitor resistance mutation in a failing raltegravir containing regimen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Physics-based scoring of protein-ligand complexes: enrichment of known inhibitors in large-scale virtual screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Antiretroviral drug resistance in non-subtype B HIV-1, HIV-2 and SIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

T-cell receptor excision circles (TREC) in SHIV 89.6p and SIVmac251 models of HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Plasma SIV RNA viral load determination by real-time quantification of product generation in reverse transcriptase-polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853490

26 November 2018

Novel HIV integrase inhibitors with anti-HIV activity: insights into integrase inhibition from docking studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20233398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the antiretroviral effects of a PEG-conjugated peptide derived from human CD38

1 reference

https://pubmed.ncbi.nlm.nih.gov/20233398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of early plasma RNA loads in different macaque species and the impact of different routes of exposure on SIV/SHIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20233398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing HIV-1 Integrase Inhibitor Binding Sites with Position-Specific Integrase-DNA Cross-Linking Assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/20233398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of HIV infection with raltegravir

1 reference

https://pubmed.ncbi.nlm.nih.gov/20233398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virtual screening application of a model of full-length HIV-1 integrase complexed with viral DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20233398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic DNA fragmentation, and its in vitro prevention by nicotinamide, in lymphocytes from HIV-1-seropositive patients and in HIV-1-infected MT-4 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20233398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20233398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-4690-7-21

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1742-4690-7-21

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

ResearchGate publication ID

0 references

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