(Q30843868)

22 August 2017

Allosteric cross-talk in chromatin can mediate drug-drug synergy (English)

1 reference

22 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Reyhan Muhammad

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Paul Dyson

series ordinal

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

6

Ursula Rothlisberger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

8

Curt A Davey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1

Zenita Adhireksan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

3

Tina Riedel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Zhujun Ma

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

language of work or name

English

0 references

publication date

30 March 2017

1 reference

22 August 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

14860

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

3 June 2020

copyright license

start time

30 March 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations.

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An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode

28 July 2018

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Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.

28 July 2018

1 reference

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Recognition of the nucleosome by chromatin factors and enzymes

28 July 2018

1 reference

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Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies

28 July 2018

1 reference

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Histone exchange, chromatin structure and the regulation of transcription

28 July 2018

1 reference

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Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome

28 July 2018

1 reference

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Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders

28 July 2018

1 reference

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The ensemble nature of allostery

28 July 2018

1 reference

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Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

The mode of action of anticancer gold-based drugs: a structural perspective

28 July 2018

1 reference

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The biological activity of auranofin: implications for novel treatment of diseases

28 July 2018

1 reference

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Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 A Resolution

28 July 2018

1 reference

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Organometallic ruthenium(II) arene compounds with antiangiogenic activity

28 July 2018

1 reference

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A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core

28 July 2018

1 reference

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Nucleosome structural studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

Structure of RCC1 chromatin factor bound to the nucleosome core particle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

Improved side-chain torsion potentials for the Amber ff99SB protein force field

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

Synergistic drug combinations tend to improve therapeutically relevant selectivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

DNA structural distortions induced by ruthenium-arene anticancer compounds.

28 July 2018

1 reference

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DNA stretching and extreme kinking in the nucleosome core

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

Refinement of the AMBER force field for nucleic acids: improving the description of alpha/gamma conformers

28 July 2018

1 reference

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Comparison of multiple Amber force fields and development of improved protein backbone parameters

28 July 2018

1 reference

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The integration of macromolecular diffraction data

28 July 2018

1 reference

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GROMACS: fast, flexible, and free

28 July 2018

1 reference

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The CCP4 suite: programs for protein crystallography

28 July 2018

1 reference

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Development and testing of a general amber force field

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

First Crystal Structure of a Medicinally Relevant Gold Protein Complex: Unexpected Binding of

28 July 2018

1 reference

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Canonical dynamics: Equilibrium phase-space distributions

28 July 2018

1 reference

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Crystal structure of the nucleosome core particle at 2.8 A resolution

28 July 2018

1 reference

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28 July 2018

1 reference

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Quantitation of the synergistic interaction of edatrexate and cisplatin in vitro

28 July 2018

1 reference

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Comparative protein modelling by satisfaction of spatial restraints

28 July 2018

1 reference

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

28 July 2018

1 reference

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Allostery in disease and in drug discovery

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

Dynamics-Driven Allostery in Protein Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

Understanding the mechanism of cytochrome P450 3A4: recent advances and remaining problems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

Effects of MacroH2A and H2A.Z on Nucleosome Dynamics as Elucidated by Molecular Dynamics Simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

Structure of trypanothione reductase from Crithidia fasciculata at 2.6 A resolution; enzyme-NADP interactions at 2.8 A resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

Drug combination studies and their synergy quantification using the Chou-Talalay method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

Molecular mechanics parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

Exposure to Metals Can Be Therapeutic

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5379107

Mechanisms of drug combinations: interaction and network perspectives

25 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

7 January 2021

In vivo anti-tumor activity of the organometallic ruthenium(ii)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) in human ovarian and colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

7 January 2021

Novel metal(ii) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

7 January 2021

Nucleosome structure and function

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

7 January 2021

[Ru(η6-p-cymene)Cl2(pta)] (pta = 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane): a water soluble compound that exhibits pH dependent DNA binding providing selectivity for diseased cells

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

7 January 2021

Influence of the Diketonato Ligand on the Cytotoxicities of [Ru(η6-p-cymene)(R2acac)(PTA)]+ Complexes (PTA = 1,3,5-triaza-7-phosphaadamantane)

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

7 January 2021

Polymorphic transitions in single crystals: A new molecular dynamics method

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

7 January 2021

Software news and updates. Carma: a molecular dynamics analysis program

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS14860

7 January 2021

Identifiers

DOI

10.1038/NCOMMS14860

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 June 2020

ADS bibcode

2017NatCo...814860A

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28358030%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference