(Q31118641)

29 June 2017

1 reference

title

Integrating structural and mutagenesis data to elucidate GPCR ligand binding (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

G protein-coupled receptor

13 May 2020

main subject

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

Kasper Skytte Harpsøe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

David E. Gloriam

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

author name string

Alexander S Hauser

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

Vignir Isberg

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

publication date

28 July 2016

1 reference

Current Opinion in Pharmacology

29 June 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

page(s)

51-58

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain

13 May 2020

cites work

1 reference

12 December 2020

Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor

1 reference

12 December 2020

Combinatorial alanine-scanning

1 reference

12 December 2020

Structure of the human histamine H1 receptor complex with doxepin

1 reference

12 December 2020

Structure of the human smoothened receptor bound to an antitumour agent

1 reference

12 December 2020

Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors

1 reference

12 December 2020

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

1 reference

12 December 2020

Structure-based discovery of beta2-adrenergic receptor ligands

1 reference

12 December 2020

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

1 reference

12 December 2020

A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors

1 reference

12 December 2020

Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors

1 reference

12 December 2020

Automated extraction and semantic analysis of mutation impacts from the biomedical literature

1 reference

12 December 2020

Ligand discovery from a dopamine D3 receptor homology model and crystal structure

1 reference

12 December 2020

Origin of the different strengths of the (i,i+4) and (i,i+3) leucine pair interactions in helices

1 reference

12 December 2020

Stabilization of G protein-coupled receptors by point mutations

1 reference

12 December 2020

Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.

1 reference

12 December 2020

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

1 reference

12 December 2020

Structure of class B GPCR corticotropin-releasing factor receptor 1

1 reference

12 December 2020

Structures of G protein-coupled receptors reveal new opportunities for drug discovery.

1 reference

12 December 2020

Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants

1 reference

12 December 2020

The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication

1 reference

12 December 2020

The Protein Mutant Database

1 reference

12 December 2020

Two disparate ligand-binding sites in the human P2Y1 receptor

1 reference

12 December 2020

Molecular signatures of G-protein-coupled receptors

1 reference

12 December 2020

Crystal structure of the β2 adrenergic receptor-Gs protein complex

1 reference

12 December 2020

Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions

1 reference

12 December 2020

Activation and allosteric modulation of a muscarinic acetylcholine receptor

1 reference

12 December 2020

Unifying family A GPCR theories of activation

1 reference

12 December 2020

Crystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal state

1 reference

12 December 2020

Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment

1 reference

12 December 2020

Structure of the agonist-bound neurotensin receptor

1 reference

12 December 2020

Genes and ligands for odorant, vomeronasal and taste receptors

1 reference

12 December 2020

GPCRDB: information system for G protein-coupled receptors

1 reference

12 December 2020

Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation

1 reference

12 December 2020

The Sequence of the Human Genome

1 reference

12 December 2020

tGRAP, the G-protein coupled receptors mutant database

1 reference

12 December 2020

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

1 reference

12 December 2020

Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design.

1 reference

12 December 2020

GPCRdb: the G protein-coupled receptor database - an introduction

1 reference

12 December 2020

Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges

1 reference

12 December 2020

Pharmacological modulation of chemokine receptor function.

1 reference

12 December 2020

Generic GPCR residue numbers - aligning topology maps while minding the gaps

1 reference

12 December 2020

Molecular Architecture of G Protein-Coupled Receptors.

1 reference

12 December 2020

Structure-based drug design for G protein-coupled receptors.

1 reference

12 December 2020

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

1 reference

12 December 2020

Pathway and mechanism of drug binding to G-protein-coupled receptors.

1 reference

12 December 2020

Structure-function of the G protein-coupled receptor superfamily

1 reference

12 December 2020

GPCRdb: an information system for G protein-coupled receptors.

1 reference

12 December 2020

The structural basis of agonist-induced activation in constitutively active rhodopsin

1 reference

12 December 2020

Extra-helical binding site of a glucagon receptor antagonist

1 reference

12 December 2020

A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors

1 reference

12 December 2020

10.1016/J.COPH.2016.07.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6910865&resulttype=core&format=json

13 May 2020

1 reference