(Q32020812)

5 July 2017

title

Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents (English)

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5 July 2017

Li Z

1

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5 July 2017

Fennie MW

2

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5 July 2017

Ganem B

3

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5 July 2017

Hancock MT

4

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5 July 2017

Kobaslija M

5

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5 July 2017

Rattendi D

6

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5 July 2017

Bacchi CJ

7

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5 July 2017

O'Sullivan MC

8

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5 July 2017

language of work or name

English

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publication date

1 January 2001

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Bioorganic & Medicinal Chemistry Letters

5 July 2017

published in

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5 July 2017

volume

11

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5 July 2017

issue

2

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5 July 2017

page(s)

251-254

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Pharmacological approaches to antitrypanosomal chemotherapy

5 July 2017

cites work

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Metabolism and functions of trypanothione in the Kinetoplastida

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7 January 2021

Molecular studies on trypanothione reductase: an antiparasitic target enzyme

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7 January 2021

Substrate specificity of the flavoprotein trypanothione disulfide reductase from Crithidia fasciculata

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7 January 2021

Evidence that trypanothione reductase is an essential enzyme in Leishmania by targeted replacement of the tryA gene locus

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7 January 2021

Disulfide-Reductase Inhibitors as Chemotherapeutic Agents: The Design of Drugs for Trypanosomiasis and Malaria

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7 January 2021

Enzymes of parasite thiol metabolism as drug targets

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7 January 2021

Synthesis of polyamine derivatives for the preparation of affinity chromatography columns for the search of new Trypanosoma cruzi targets

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7 January 2021

Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs

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7 January 2021

Trypanocidal Bisbenzylisoquinoline Alkaloids are Inhibitors of Trypanothione Reductase

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7 January 2021

Rational design of selective ligands for trypanothione reductase fromtrypanosoma cruzStructural effects on the inhibition by dibenzazepines based on imipramine

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7 January 2021

Inhibition of Trypanosoma cruzi trypanothione reductase by crystal violet

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7 January 2021

Rationally designed selective inhibitors of trypanothione reductase. Phenothiazines and related tricyclics as lead structures

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7 January 2021

Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors

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7 January 2021

A General Approach to the Synthesis of Polyamine Linked-Monoindolylmaleimides, a New Series of Trypanothione Reductase Inhibitors

1 reference

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7 January 2021

Structure-activity relationships in 2-aminodiphenylsulfides against trypanothione reductase from Trypanosoma cruzi

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7 January 2021

New spermine and spermidine derivatives as potent inhibitors of Trypanosoma cruzi Trypanothione Reductase

1 reference

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7 January 2021

2-Amino diphenylsulfides as inhibitors of trypanothione reductase: modification of the side chain

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7 January 2021

Inhibiting effects of spermidine derivatives on Trypanosoma cruzi trypanothione reductase

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7 January 2021

Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase.

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7 January 2021

Polyamine derivatives as inhibitors of trypanothione reductase and assessment of their trypanocidal activities

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7 January 2021

Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures(1).

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7 January 2021

Expression of Trypanosoma congolense trypanothione reductase in Escherichia coli: overproduction, purification, and characterization

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7 January 2021

Cloning, sequencing, overproduction and purification of trypanothione reductase from Trypanosoma cruzi.

1 reference

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7 January 2021

Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases

1 reference

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7 January 2021

Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors

1 reference

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7 January 2021

Crystal structure of the Trypanosoma cruzi trypanothione reductase.mepacrine complex

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7 January 2021

Cation-pi bonding and amino-aromatic interactions in the biomolecular recognition of substituted ammonium ligands

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7 January 2021

10.1016/S0960-894X(00)00643-0

Identifiers

DOI

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5 July 2017

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